Anti‐cancer potential of selenium‐ and tellurium‐containing species: opportunities abound!
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- Hoi‐Ling Seng
- Department of Chemistry University of Malaya 50603 Kuala Lumpur Malaysia
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- Edward R. T. Tiekink
- Department of Chemistry University of Malaya 50603 Kuala Lumpur Malaysia
説明
<jats:p>An overview highlighting the anti‐cancer potential of (bio‐essential) selenium‐ and tellurium‐containing species, with an emphasis on biological targets and mechanisms of action, is presented. Studies thus far have focused on selenium(II) compounds (along with – to a lesser extent – inorganic selenium and selenium nanoparticles) which often successfully exploit the inherent anti‐oxidizing ability of selenium. Significantly less work has been conducted in developing anti‐cancer tellurium compounds, yet two tellurium(IV) species are proven, clinically, as anti‐cancer agents. Given the prevalence of the disease and the accumulated insights into mechanisms of action, the continued development of selenium‐ and tellurium‐containing molecules is an area deserving greater attention. Copyright © 2012 John Wiley & Sons, Ltd.</jats:p>
収録刊行物
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- Applied Organometallic Chemistry
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Applied Organometallic Chemistry 26 (12), 655-662, 2012-12
Wiley
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詳細情報 詳細情報について
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- CRID
- 1362262945207295872
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- DOI
- 10.1002/aoc.2928
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- ISSN
- 10990739
- 02682605
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- データソース種別
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- Crossref