Safety of Statins

DOI Web Site 11 Citations
  • Stefano Bellosta
    From the Department of Pharmacological Sciences, University of Milan, Milan, Italy.
  • Rodolfo Paoletti
    From the Department of Pharmacological Sciences, University of Milan, Milan, Italy.
  • Alberto Corsini
    From the Department of Pharmacological Sciences, University of Milan, Milan, Italy.

Bibliographic Information

Other Title
  • Focus on Clinical Pharmacokinetics and Drug Interactions

Description

<jats:p>Statin monotherapy is generally well tolerated, with a low frequency of adverse events. The most important adverse effects associated with statins are myopathy and an asymptomatic increase in hepatic transaminases, both of which occur infrequently. Because statins are prescribed on a long-term basis, however, possible interactions with other drugs deserve particular attention, as many patients will typically receive pharmacological therapy for concomitant conditions during the course of statin treatment. This review summarizes the pharmacokinetic properties of statins and emphasizes their clinically relevant drug interactions.</jats:p>

Journal

  • Circulation

    Circulation 109 (23_suppl_1), III50-, 2004-06-15

    Ovid Technologies (Wolters Kluwer Health)

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