Synthesis, Corticotropin-Releasing Factor Receptor Binding Affinity, and Pharmacokinetic Properties of Triazolo-, Imidazo-, and Pyrrolopyrimidines and -pyridines

  • Robert J. Chorvat
    Departments of Chemical and Physical Sciences and of Biological Sciences, DuPont Pharmaceuticals Company, Experimental Station, P.O. Box 80500, Wilmington, Delaware 19880-0500, and Drug Metabolism and Pharmacokinetic Section, Stine-Haskell Research Center, Newark, Delaware 19714
  • Rajagopal Bakthavatchalam
    Departments of Chemical and Physical Sciences and of Biological Sciences, DuPont Pharmaceuticals Company, Experimental Station, P.O. Box 80500, Wilmington, Delaware 19880-0500, and Drug Metabolism and Pharmacokinetic Section, Stine-Haskell Research Center, Newark, Delaware 19714
  • James P. Beck
    Departments of Chemical and Physical Sciences and of Biological Sciences, DuPont Pharmaceuticals Company, Experimental Station, P.O. Box 80500, Wilmington, Delaware 19880-0500, and Drug Metabolism and Pharmacokinetic Section, Stine-Haskell Research Center, Newark, Delaware 19714
  • Paul J. Gilligan
    Departments of Chemical and Physical Sciences and of Biological Sciences, DuPont Pharmaceuticals Company, Experimental Station, P.O. Box 80500, Wilmington, Delaware 19880-0500, and Drug Metabolism and Pharmacokinetic Section, Stine-Haskell Research Center, Newark, Delaware 19714
  • Richard G. Wilde
    Departments of Chemical and Physical Sciences and of Biological Sciences, DuPont Pharmaceuticals Company, Experimental Station, P.O. Box 80500, Wilmington, Delaware 19880-0500, and Drug Metabolism and Pharmacokinetic Section, Stine-Haskell Research Center, Newark, Delaware 19714
  • Anthony J. Cocuzza
    Departments of Chemical and Physical Sciences and of Biological Sciences, DuPont Pharmaceuticals Company, Experimental Station, P.O. Box 80500, Wilmington, Delaware 19880-0500, and Drug Metabolism and Pharmacokinetic Section, Stine-Haskell Research Center, Newark, Delaware 19714
  • Frank W. Hobbs
    Departments of Chemical and Physical Sciences and of Biological Sciences, DuPont Pharmaceuticals Company, Experimental Station, P.O. Box 80500, Wilmington, Delaware 19880-0500, and Drug Metabolism and Pharmacokinetic Section, Stine-Haskell Research Center, Newark, Delaware 19714
  • Robert S. Cheeseman
    Departments of Chemical and Physical Sciences and of Biological Sciences, DuPont Pharmaceuticals Company, Experimental Station, P.O. Box 80500, Wilmington, Delaware 19880-0500, and Drug Metabolism and Pharmacokinetic Section, Stine-Haskell Research Center, Newark, Delaware 19714
  • Matthew Curry
    Departments of Chemical and Physical Sciences and of Biological Sciences, DuPont Pharmaceuticals Company, Experimental Station, P.O. Box 80500, Wilmington, Delaware 19880-0500, and Drug Metabolism and Pharmacokinetic Section, Stine-Haskell Research Center, Newark, Delaware 19714
  • Joseph P. Rescinito
    Departments of Chemical and Physical Sciences and of Biological Sciences, DuPont Pharmaceuticals Company, Experimental Station, P.O. Box 80500, Wilmington, Delaware 19880-0500, and Drug Metabolism and Pharmacokinetic Section, Stine-Haskell Research Center, Newark, Delaware 19714
  • Paul Krenitsky
    Departments of Chemical and Physical Sciences and of Biological Sciences, DuPont Pharmaceuticals Company, Experimental Station, P.O. Box 80500, Wilmington, Delaware 19880-0500, and Drug Metabolism and Pharmacokinetic Section, Stine-Haskell Research Center, Newark, Delaware 19714
  • Dennis Chidester
    Departments of Chemical and Physical Sciences and of Biological Sciences, DuPont Pharmaceuticals Company, Experimental Station, P.O. Box 80500, Wilmington, Delaware 19880-0500, and Drug Metabolism and Pharmacokinetic Section, Stine-Haskell Research Center, Newark, Delaware 19714
  • Jerry A. Yarem
    Departments of Chemical and Physical Sciences and of Biological Sciences, DuPont Pharmaceuticals Company, Experimental Station, P.O. Box 80500, Wilmington, Delaware 19880-0500, and Drug Metabolism and Pharmacokinetic Section, Stine-Haskell Research Center, Newark, Delaware 19714
  • John D. Klaczkiewicz
    Departments of Chemical and Physical Sciences and of Biological Sciences, DuPont Pharmaceuticals Company, Experimental Station, P.O. Box 80500, Wilmington, Delaware 19880-0500, and Drug Metabolism and Pharmacokinetic Section, Stine-Haskell Research Center, Newark, Delaware 19714
  • C. Nicholas Hodge
    Departments of Chemical and Physical Sciences and of Biological Sciences, DuPont Pharmaceuticals Company, Experimental Station, P.O. Box 80500, Wilmington, Delaware 19880-0500, and Drug Metabolism and Pharmacokinetic Section, Stine-Haskell Research Center, Newark, Delaware 19714
  • Paul E. Aldrich
    Departments of Chemical and Physical Sciences and of Biological Sciences, DuPont Pharmaceuticals Company, Experimental Station, P.O. Box 80500, Wilmington, Delaware 19880-0500, and Drug Metabolism and Pharmacokinetic Section, Stine-Haskell Research Center, Newark, Delaware 19714
  • Zelda R. Wasserman
    Departments of Chemical and Physical Sciences and of Biological Sciences, DuPont Pharmaceuticals Company, Experimental Station, P.O. Box 80500, Wilmington, Delaware 19880-0500, and Drug Metabolism and Pharmacokinetic Section, Stine-Haskell Research Center, Newark, Delaware 19714
  • Christine H. Fernandez
    Departments of Chemical and Physical Sciences and of Biological Sciences, DuPont Pharmaceuticals Company, Experimental Station, P.O. Box 80500, Wilmington, Delaware 19880-0500, and Drug Metabolism and Pharmacokinetic Section, Stine-Haskell Research Center, Newark, Delaware 19714
  • Robert Zaczek
    Departments of Chemical and Physical Sciences and of Biological Sciences, DuPont Pharmaceuticals Company, Experimental Station, P.O. Box 80500, Wilmington, Delaware 19880-0500, and Drug Metabolism and Pharmacokinetic Section, Stine-Haskell Research Center, Newark, Delaware 19714
  • Lawrence W. Fitzgerald
    Departments of Chemical and Physical Sciences and of Biological Sciences, DuPont Pharmaceuticals Company, Experimental Station, P.O. Box 80500, Wilmington, Delaware 19880-0500, and Drug Metabolism and Pharmacokinetic Section, Stine-Haskell Research Center, Newark, Delaware 19714
  • Shiew-Mei Huang
    Departments of Chemical and Physical Sciences and of Biological Sciences, DuPont Pharmaceuticals Company, Experimental Station, P.O. Box 80500, Wilmington, Delaware 19880-0500, and Drug Metabolism and Pharmacokinetic Section, Stine-Haskell Research Center, Newark, Delaware 19714
  • Helen L. Shen
    Departments of Chemical and Physical Sciences and of Biological Sciences, DuPont Pharmaceuticals Company, Experimental Station, P.O. Box 80500, Wilmington, Delaware 19880-0500, and Drug Metabolism and Pharmacokinetic Section, Stine-Haskell Research Center, Newark, Delaware 19714
  • Y. Nancy Wong
    Departments of Chemical and Physical Sciences and of Biological Sciences, DuPont Pharmaceuticals Company, Experimental Station, P.O. Box 80500, Wilmington, Delaware 19880-0500, and Drug Metabolism and Pharmacokinetic Section, Stine-Haskell Research Center, Newark, Delaware 19714
  • Ben M. Chien
    Departments of Chemical and Physical Sciences and of Biological Sciences, DuPont Pharmaceuticals Company, Experimental Station, P.O. Box 80500, Wilmington, Delaware 19880-0500, and Drug Metabolism and Pharmacokinetic Section, Stine-Haskell Research Center, Newark, Delaware 19714
  • Check Y. Quon
    Departments of Chemical and Physical Sciences and of Biological Sciences, DuPont Pharmaceuticals Company, Experimental Station, P.O. Box 80500, Wilmington, Delaware 19880-0500, and Drug Metabolism and Pharmacokinetic Section, Stine-Haskell Research Center, Newark, Delaware 19714
  • Argyrios Arvanitis
    Departments of Chemical and Physical Sciences and of Biological Sciences, DuPont Pharmaceuticals Company, Experimental Station, P.O. Box 80500, Wilmington, Delaware 19880-0500, and Drug Metabolism and Pharmacokinetic Section, Stine-Haskell Research Center, Newark, Delaware 19714

書誌事項

公開日
1999-02-17
DOI
  • 10.1021/jm980224g
公開者
American Chemical Society (ACS)

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