The Hoesch Test: Bedside Screening for Urinary Porphobilinogen in Patients with Suspected Porphyria
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- Joel Lamon
- Department of Internal Medicine, University of Southern California School of Medicine, Los Angeles, Calif. 90033; and the Department of Chemical Pathology, Svendborg Hospital, 5700 Svendborg, Denmark
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- Torben K With
- Department of Internal Medicine, University of Southern California School of Medicine, Los Angeles, Calif. 90033; and the Department of Chemical Pathology, Svendborg Hospital, 5700 Svendborg, Denmark
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- Allan G Redeker
- Department of Internal Medicine, University of Southern California School of Medicine, Los Angeles, Calif. 90033; and the Department of Chemical Pathology, Svendborg Hospital, 5700 Svendborg, Denmark
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説明
<jats:title>Abstract</jats:title> <jats:p>A little-known procedure for porphobilinogen screening, the Hoesch test, was examined for sensitivity, specificity, and utility as compared to the Watson-Schwartz test. The data demonstrate that its sensitivity is similar to that of the Watson-Schwartz test. The Hoesch test, however, is without false-positive reactions secondary to urobilinogen, and its simplicity makes it easier to use and more easily interpretable. We conclude that the Hoesch test should replace the Watson-Schwartz test for urine porphobilinogen screening in suspected cases of acute intermittent and variegate porphyria.</jats:p>
収録刊行物
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- Clinical Chemistry
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Clinical Chemistry 20 (11), 1438-1440, 1974-11-01
Oxford University Press (OUP)
