Tula virus: a newly detected hantavirus carried by European common voles

DOI Web Site 被引用文献2件
  • A Plyusnin
    Haartman Institute, Department of Virology, Helsinki University, Finland.
  • O Vapalahti
    Haartman Institute, Department of Virology, Helsinki University, Finland.
  • H Lankinen
    Haartman Institute, Department of Virology, Helsinki University, Finland.
  • H Lehväslaiho
    Haartman Institute, Department of Virology, Helsinki University, Finland.
  • N Apekina
    Haartman Institute, Department of Virology, Helsinki University, Finland.
  • Y Myasnikov
    Haartman Institute, Department of Virology, Helsinki University, Finland.
  • H Kallio-Kokko
    Haartman Institute, Department of Virology, Helsinki University, Finland.
  • H Henttonen
    Haartman Institute, Department of Virology, Helsinki University, Finland.
  • A Lundkvist
    Haartman Institute, Department of Virology, Helsinki University, Finland.
  • M Brummer-Korvenkontio
    Haartman Institute, Department of Virology, Helsinki University, Finland.

書誌事項

公開日
1994-12
権利情報
  • https://journals.asm.org/non-commercial-tdm-license
DOI
  • 10.1128/jvi.68.12.7833-7839.1994
公開者
American Society for Microbiology

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説明

<jats:p>A novel hantavirus has been discovered in European common voles, Microtus arvalis and Microtus rossiaemeridionalis. According to sequencing data for the genomic RNA S segment and nucleocapsid protein and data obtained by immunoblotting with a panel of monoclonal antibodies, the virus, designated Tula virus, is a distinct novel member of the genus Hantavirus. Phylogenetic analyses of Tula virus indicate that it is most closely related to Prospect Hill, Puumala, and Muerto Canyon viruses. The results support the view that the evolution of hantaviruses follows that of their primary carriers. Comparison of strains circulating within a local rodent population revealed a genetic drift via accumulation of base substitutions and deletions or insertions. The Tula virus population from individual animals is represented by quasispecies, indicating the potential for rapid evolution of the agent.</jats:p>

収録刊行物

  • Journal of Virology

    Journal of Virology 68 (12), 7833-7839, 1994-12

    American Society for Microbiology

被引用文献 (2)*注記

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