Oxidative stress in skeletal muscle atrophied by immobiIization
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説明
The production of free radicals in the mitochondria has been investigated more than that in other organelles, and is believed to play a major role in oxidative stress in the cell. In the muscle, the increase in muscular activity enhances the oxygen consumption and increased oxygen consumption accelerates the production of free radicals in the mitochondria (Asayama and Kato, 1990). In view of this, it was believed, with no consideration for the production of free radicals in the cytoplasm, that the oxidative stress in the muscle might parallel muscular activity, i.e. the oxidative stress might decrease in muscular atrophy. This may be the reason for the small number of reports about oxidative stress during muscular atrophy of disuse, although numerous studies have been carried out in this decade on oxidative stress during exercise.
収録刊行物
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- Acta Physiologica Scandinavica
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Acta Physiologica Scandinavica 142 (4), 527-528, 1991-08
Wiley