Understanding the impact of sex and gender in Alzheimer's disease: A call to action
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- Rebecca A. Nebel
- Scientific Programs Society for Women's Health Research (SWHR®) Washington DC USA
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- Neelum T. Aggarwal
- Department of Neurological Sciences and the Rush Alzheimer's Disease Center Rush University Medical Center Chicago IL USA
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- Lisa L. Barnes
- Department of Neurological Sciences and the Rush Alzheimer's Disease Center Rush University Medical Center Chicago IL USA
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- Aimee Gallagher
- Scientific Programs Society for Women's Health Research (SWHR®) Washington DC USA
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- Jill M. Goldstein
- Department of Psychiatry Harvard Medical School and Massachusetts General Hospital Boston MA USA
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- Kejal Kantarci
- Department of Radiology Mayo Clinic Rochester MN USA
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- Monica P. Mallampalli
- Scientific Programs Society for Women's Health Research (SWHR®) Washington DC USA
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- Elizabeth C. Mormino
- Department of Neurology and Neurological Sciences Stanford University Stanford CA USA
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- Laura Scott
- Cellular and Molecular Medicine Program Johns Hopkins University Baltimore MD USA
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- Wai Haung Yu
- Department of Pathology and Cell Biology Taub Institute for Research on Alzheimer's Disease and the Aging Brain Columbia University New York NY USA
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- Pauline M. Maki
- Department of Psychology University of Illinois at Chicago Chicago IL USA
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- Michelle M. Mielke
- Department of Epidemiology Mayo Clinic Rochester MN USA
説明
<jats:title>Abstract</jats:title><jats:sec><jats:title>Introduction</jats:title><jats:p>Precision medicine methodologies and approaches have advanced our understanding of the clinical presentation, development, progression, and management of Alzheimer's disease (AD) dementia. However, sex and gender have not yet been adequately integrated into many of these approaches.</jats:p></jats:sec><jats:sec><jats:title>Methods</jats:title><jats:p>The Society for Women's Health Research Interdisciplinary Network on AD, comprised of an expert panel of scientists and clinicians, reviewed ongoing and published research related to sex and gender differences in AD.</jats:p></jats:sec><jats:sec><jats:title>Results</jats:title><jats:p>The current review is a result of this Network's efforts and aims to: (1) highlight the current state‐of‐the‐science in the AD field on sex and gender differences; (2) address knowledge gaps in assessing sex and gender differences; and (3) discuss 12 priority areas that merit further research.</jats:p></jats:sec><jats:sec><jats:title>Discussion</jats:title><jats:p>The exclusion of sex and gender has impeded faster advancement in the detection, treatment, and care of AD across the clinical spectrum. Greater attention to these differences will improve outcomes for both sexes.</jats:p></jats:sec>
収録刊行物
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- Alzheimer's & Dementia
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Alzheimer's & Dementia 14 (9), 1171-1183, 2018-06-12
Wiley
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詳細情報 詳細情報について
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- CRID
- 1362544418713907200
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- ISSN
- 15525279
- 15525260
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- Web Site
- https://api.elsevier.com/content/article/PII:S1552526018301304?httpAccept=text/xml
- https://api.elsevier.com/content/article/PII:S1552526018301304?httpAccept=text/plain
- https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1016%2Fj.jalz.2018.04.008
- https://onlinelibrary.wiley.com/doi/pdf/10.1016/j.jalz.2018.04.008
- https://onlinelibrary.wiley.com/doi/full-xml/10.1016/j.jalz.2018.04.008
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