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- Olga Castaner
- Cardiovascular Risk and Nutrition Research Group, Hospital del Mar Research Institute (IMIM), Barcelona, Spain
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- Albert Goday
- CIBER de Fisiopatología de la Obesidad y Nutrición (CIBEROBN), Santiago de Compostela, Spain
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- Yong-Moon Park
- Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC, USA
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- Seung-Hwan Lee
- Division of Endocrinology & Metabolism, Department of Internal Medicine, Seoul St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea
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- Faidon Magkos
- Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore (NUS) and Clinical Nutrition Research Centre (CNRC), Singapore Institute for Clinical Sciences (SICS), Agency for Science, Technology and Research (A∗STAR), Singapore
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- Sue-Anne Toh Ee Shiow
- Yong Loo Lin School of Medicine, National University of Singapore, Singapore
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- Helmut Schröder
- Cardiovascular Risk and Nutrition Research Group, Hospital del Mar Research Institute (IMIM), Barcelona, Spain
抄録
<jats:p>Gut microbiome has been identified in the past decade as an important factor involved in obesity, but the magnitude of its contribution to obesity and its related comorbidities is still uncertain. Among the vast quantity of factors attributed to obesity, environmental, dietary, lifestyle, genetic, and others, the microbiome has aroused curiosity, and the scientific community has published many original articles. Most of the studies related to microbiome and obesity have been reported based on the associations between microbiota and obesity, and the in-depth study of the mechanisms related has been studied mainly in rodents and exceptionally in humans. Due to the quantity and diverse information published, the need of reviews is mandatory to recapitulate the relevant achievements. In this systematic review, we provide an overview of the current evidence on the association between intestinal microbiota and obesity. Additionally, we analyze the effects of an extreme weight loss intervention such as bariatric surgery on gut microbiota. The review is divided into 2 sections: first, the association of obesity and related metabolic disorders with different gut microbiome profiles, including metagenomics studies, and second, changes on gut microbiome after an extreme weight loss intervention such as bariatric surgery.</jats:p>
収録刊行物
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- International Journal of Endocrinology
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International Journal of Endocrinology 2018 1-9, 2018
Hindawi Limited