Fourier transform ion cyclotron resonance (FT ICR) mass spectrometry: Theory and simulations

  • Eugene N. Nikolaev
    Institute for Energy Problems of Chemical Physics Russian Academy of Sciences Leninskij pr. 38 k. 2 119334 Moscow Russia
  • Yury I. Kostyukevich
    Institute for Energy Problems of Chemical Physics Russian Academy of Sciences Leninskij pr. 38 k. 2 119334 Moscow Russia
  • Gleb N. Vladimirov
    Institute for Energy Problems of Chemical Physics Russian Academy of Sciences Leninskij pr. 38 k. 2 119334 Moscow Russia

書誌事項

公開日
2014-02-10
権利情報
  • http://onlinelibrary.wiley.com/termsAndConditions#vor
DOI
  • 10.1002/mas.21422
公開者
Wiley

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説明

<jats:sec><jats:label/><jats:p>Fourier transform ion cyclotron resonance (FT ICR) mass spectrometer offers highest resolving power and mass accuracy among all types of mass spectrometers. Its unique analytical characteristics made FT ICR important tool for proteomics, metabolomics, petroleomics, and investigation of complex mixtures. Signal acquisition in FT ICR MS takes long time (up to minutes). During this time ion–ion interaction considerably affects ion motion and result in decreasing of the resolving power. Understanding of those effects required complicated theory and supercomputer simulations but culminated in the invention of the ion trap with dynamic harmonization which demonstrated the highest resolving power ever achieved. In this review we summarize latest achievements in theory and simulation of FT ICR mass spectrometers. © 2014 Wiley Periodicals, Inc. Mass Spec Rev 35:219–258, 2016.</jats:p></jats:sec>

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