Telomere-Led Premeiotic Chromosome Movement in Fission Yeast

DOI Web Site 被引用文献63件
  • Yuji Chikashige
    Kansai Advanced Research Center, Communications Research Laboratory, 588-2 Iwaoka, lwaoka-cho, Nishi-ku, Kobe 651-24, Japan
  • Da-Qiao Ding
    Kansai Advanced Research Center, Communications Research Laboratory, 588-2 Iwaoka, lwaoka-cho, Nishi-ku, Kobe 651-24, Japan
  • Hironori Funabiki
    Department of Biophysics, Faculty of Science, Kyoto University, Kyoto 606, Japan.
  • Tokuko Haraguchi
    Kansai Advanced Research Center, Communications Research Laboratory, 588-2 Iwaoka, lwaoka-cho, Nishi-ku, Kobe 651-24, Japan
  • Shinro Mashiko
    Kansai Advanced Research Center, Communications Research Laboratory, 588-2 Iwaoka, lwaoka-cho, Nishi-ku, Kobe 651-24, Japan
  • Mitsuhiro Yanagida
    Department of Biophysics, Faculty of Science, Kyoto University, Kyoto 606, Japan.
  • Yasushi Hiraoka
    Kansai Advanced Research Center, Communications Research Laboratory, 588-2 Iwaoka, lwaoka-cho, Nishi-ku, Kobe 651-24, Japan

抄録

<jats:p>The movement of chromosomes that precedes meiosis was observed in living cells of fission yeast by fluorescence microscopy. Further analysis by in situ hybridization revealed that the telomeres remain clustered at the leading end of premeiotic chromosome movement, unlike mitotic chromosome movement in which the centromere leads. Once meiotic chromosome segregation starts, however, centromeres resume the leading position in chromosome movement, as they do in mitosis. Although the movement of the telomere first has not been observed before, the clustering of telomeres is reminiscent of the bouquet structure of meiotic-prophase chromosomes observed in higher eukaryotes, which suggests that telomeres perform specific functions required for premeiotic chromosomal events generally in eukaryotes.</jats:p>

収録刊行物

  • Science

    Science 264 (5156), 270-273, 1994-04-08

    American Association for the Advancement of Science (AAAS)

被引用文献 (63)*注記

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