Comparative Genomic Analysis of Multidrug-Resistant Pseudomonas aeruginosa Clinical Isolates VRFPA06 and VRFPA08 with VRFPA07

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  • Nandagopal Murugan
    Dept. of Microbiology, L & T Microbiology Research Centre, Vision Research Foundation, Sankara Nethralaya, Chennai, Tamil Nadu, India
  • Jambulingam Malathi
    Dept. of Microbiology, L & T Microbiology Research Centre, Vision Research Foundation, Sankara Nethralaya, Chennai, Tamil Nadu, India
  • Vetrivel Umashankar
    Centre for Bioinformatics, Vision Research Foundation, Sankara Nethralaya, Chennai, Tamil Nadu, India
  • Hajib Narahari Rao Madhavan
    Dept. of Microbiology, L & T Microbiology Research Centre, Vision Research Foundation, Sankara Nethralaya, Chennai, Tamil Nadu, India

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<jats:title>ABSTRACT</jats:title> <jats:p> <jats:named-content content-type="genus-species">Pseudomonas aeruginosa</jats:named-content> isolates harboring acquired drug-resistant genes lead to increased mortality. Here, we have sequenced and annotated the genomes of two multidrug-resistant (MDR) <jats:named-content content-type="genus-species">P. aeruginosa</jats:named-content> isolates and a susceptible <jats:named-content content-type="genus-species">P. aeruginosa</jats:named-content> clinical isolate evidencing divergent antibiotic susceptibilities. Genomic analysis showed insight on the different genomic strategies adapted by <jats:named-content content-type="genus-species">P. aeruginosa</jats:named-content> to combat antimicrobial effects. </jats:p>

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