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- Caren Chancey
- United States Food and Drug Administration, Center for Biologics Evaluation and Research, Silver Spring, MD 20993-0002, USA
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- Andriyan Grinev
- United States Food and Drug Administration, Center for Biologics Evaluation and Research, Silver Spring, MD 20993-0002, USA
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- Evgeniya Volkova
- United States Food and Drug Administration, Center for Biologics Evaluation and Research, Silver Spring, MD 20993-0002, USA
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- Maria Rios
- United States Food and Drug Administration, Center for Biologics Evaluation and Research, Silver Spring, MD 20993-0002, USA
説明
<jats:p>Since its initial isolation in Uganda in 1937 through the present, West Nile virus (WNV) has become an important cause of human and animal disease worldwide. WNV, an enveloped virus of the genus<jats:italic>Flavivirus</jats:italic>, is naturally maintained in an enzootic cycle between birds and mosquitoes, with occasional epizootic spillover causing disease in humans and horses. The mosquito vectors for WNV are widely distributed worldwide, and the known geographic range of WNV transmission and disease has continued to increase over the past 77 years. While most human infections with WNV are asymptomatic, severe neurological disease may develop resulting in long-term sequelae or death. Surveillance and preventive measures are an ongoing need to reduce the public health impact of WNV in areas with the potential for transmission.</jats:p>
収録刊行物
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- BioMed Research International
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BioMed Research International 2015 1-20, 2015
Hindawi Limited