Bioimaging TOF‐SIMS: localization of cholesterol in rat kidney sections

DOI Web Site Web Site 2 Citations

Search this article

Description

<jats:p>Rat kidneys were sectioned by cryoultramicrotomy and dried at room temperature. The samples were covered with a thin silver layer and analyzed in an imaging TOF‐SIMS instrument equipped with a Ga<jats:sup>+</jats:sup>‐source. The cholesterol signal showed a high concentration in the nuclear areas of the epithelial cells and a lower concentration over areas representing the basal lamina of renal tubules. A more diffuse distribution of cholesterol was also found over areas representing the cytoplasm or plasma membrane of the epithelial cells.</jats:p>

Journal

  • FEBS Letters

    FEBS Letters 566 (1-3), 291-293, 2004-05-10

    Wiley

Citations (2)*help

See more

Report a problem

Back to top