DNA gyrase: an enzyme that introduces superhelical turns into DNA.

DOI Web Site 被引用文献7件

書誌事項

公開日
1976-11
DOI
  • 10.1073/pnas.73.11.3872
公開者
Proceedings of the National Academy of Sciences

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説明

<jats:p>Relaxed closed-circular DNA is converted to negatively supercoiled DNA by DNA gyrase. This enzyme has been purified from Escherichia coli cells. The reaction requires ATP and Mg++ and is stimulated by spermidine. The enzyme acts equally well on relaxed closed-circular colicin E1, phage lambda, and simian virus 40 DNA. The final superhelix density of the DNA can be considerably greater than that found in intracellularly supercoiled DNA.</jats:p>

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