Advances in biomaterials for adipose tissue reconstruction in plastic surgery
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- Zhiyu Peng
- Department of Burn and Plastic Surgery , West China School of Medicine , West China Hospital , Sichuan University , 610041 , Chengdu , China
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- Pei Tang
- Department of Burn and Plastic Surgery , West China School of Medicine , West China Hospital , Sichuan University , 610041 , Chengdu , China
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- Li Zhao
- Department of Health Policy and Management , West China School of Public Health , West China Fourth Hospital , Sichuan University , 610041 , Chengdu , China
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- Lina Wu
- National Engineering Research Center for Biomaterials , Sichuan University , 610064 , Chengdu , China
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- Xiujuan Xu
- National Engineering Research Center for Biomaterials , Sichuan University , 610064 , Chengdu , China
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- Haoyuan Lei
- National Engineering Research Center for Biomaterials , Sichuan University , 610064 , Chengdu , China
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- Min Zhou
- Department of Burn and Plastic Surgery , West China School of Medicine , West China Hospital , Sichuan University , 610041 , Chengdu , China
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- Changchun Zhou
- National Engineering Research Center for Biomaterials , Sichuan University , 610064 , Chengdu , China
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- Zhengyong Li
- Department of Burn and Plastic Surgery , West China School of Medicine , West China Hospital , Sichuan University , 610041 , Chengdu , China
説明
<jats:title>Abstract</jats:title> <jats:p>Adipose tissue reconstruction is an important technique for soft tissue defects caused by facial plastic surgery and trauma. Adipose tissue reconstruction can be repaired by fat transplantation and biomaterial filling, but there are some problems in fat transplantation, such as second operation and limited resources. The application of advanced artificial biomaterials is a promising strategy. In this paper, injectable biomaterials and three-dimensional (3D) tissue-engineered scaffold materials for adipose tissue reconstruction in plastic surgery are reviewed. Injectable biomaterials include natural biomaterials and artificial biomaterials, which generally have problems such as high absorptivity of fillers, repeated injection, and rejection. In recent years, the technology of new 3D tissue-engineering scaffold materials with adipose-derived stem cells (ADSCs) and porous scaffold as the core has made good progress in fat reconstruction, which is expected to solve the current problem of clinical adipose tissue reconstruction, and various biomaterials preparation technology and transformation research also provide the basis for clinical transformation of fat tissue reconstruction.</jats:p>
収録刊行物
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- Nanotechnology Reviews
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Nanotechnology Reviews 9 (1), 385-395, 2020-01-01
Walter de Gruyter GmbH