tRNA Modification Profiles and Codon-Decoding Strategies in Methanocaldococcus jannaschii

  • Ningxi Yu
    Rieveschl Laboratories for Mass Spectrometry, Department of Chemistry, University of Cincinnati, Cincinnati, Ohio, USA
  • Manasses Jora
    Rieveschl Laboratories for Mass Spectrometry, Department of Chemistry, University of Cincinnati, Cincinnati, Ohio, USA
  • Beulah Solivio
    Rieveschl Laboratories for Mass Spectrometry, Department of Chemistry, University of Cincinnati, Cincinnati, Ohio, USA
  • Priti Thakur
    Rieveschl Laboratories for Mass Spectrometry, Department of Chemistry, University of Cincinnati, Cincinnati, Ohio, USA
  • Carlos G. Acevedo-Rocha
    Max Planck Institute for Terrestrial Microbiology, Marburg, Germany
  • Lennart Randau
    Max Planck Institute for Terrestrial Microbiology, Marburg, Germany
  • Valérie de Crécy-Lagard
    Department of Microbiology and Cell Science, Institute of Food and Agricultural Sciences, University of Florida, Gainesville, Florida, USA
  • Balasubrahmanyam Addepalli
    Rieveschl Laboratories for Mass Spectrometry, Department of Chemistry, University of Cincinnati, Cincinnati, Ohio, USA
  • Patrick A. Limbach
    Rieveschl Laboratories for Mass Spectrometry, Department of Chemistry, University of Cincinnati, Cincinnati, Ohio, USA

説明

<jats:p> While many posttranscriptional modifications in <jats:named-content content-type="genus-species">M. jannaschii</jats:named-content> tRNAs are also found in bacteria and eukaryotes, several that are unique to archaea were identified. By RNA modification mapping, the modification profiles of <jats:named-content content-type="genus-species">M. jannaschii</jats:named-content> tRNA anticodon loops were characterized, allowing a comparative analysis with <jats:named-content content-type="genus-species">H. volcanii</jats:named-content> modification profiles as well as a general comparison with bacterial and eukaryotic decoding strategies. This general comparison reveals that <jats:named-content content-type="genus-species">M. jannaschii</jats:named-content> , like <jats:named-content content-type="genus-species">H. volcanii</jats:named-content> , follows codon-decoding strategies similar to those used by bacteria, although position 37 appears to be modified to a greater extent than seen in <jats:named-content content-type="genus-species">H. volcanii</jats:named-content> . </jats:p>

収録刊行物

被引用文献 (2)*注記

もっと見る

詳細情報 詳細情報について

問題の指摘

ページトップへ