CCND2 rearrangements are the most frequent genetic events in cyclin D1− mantle cell lymphoma
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- Itziar Salaverria
- Department of Pathology, Hematopathology Unit, Hospital Clínic, Institut d'Investigacions Biomèdiques August Pi i Sunyer, University of Barcelona, Barcelona, Spain;
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- Cristina Royo
- Department of Pathology, Hematopathology Unit, Hospital Clínic, Institut d'Investigacions Biomèdiques August Pi i Sunyer, University of Barcelona, Barcelona, Spain;
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- Alejandra Carvajal-Cuenca
- Department of Pathology, Hematopathology Unit, Hospital Clínic, Institut d'Investigacions Biomèdiques August Pi i Sunyer, University of Barcelona, Barcelona, Spain;
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- Guillem Clot
- Department of Pathology, Hematopathology Unit, Hospital Clínic, Institut d'Investigacions Biomèdiques August Pi i Sunyer, University of Barcelona, Barcelona, Spain;
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- Alba Navarro
- Department of Pathology, Hematopathology Unit, Hospital Clínic, Institut d'Investigacions Biomèdiques August Pi i Sunyer, University of Barcelona, Barcelona, Spain;
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- Alejandra Valera
- Department of Pathology, Hematopathology Unit, Hospital Clínic, Institut d'Investigacions Biomèdiques August Pi i Sunyer, University of Barcelona, Barcelona, Spain;
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- Joo Y. Song
- Laboratory of Pathology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD;
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- Renata Woroniecka
- Cytogenetic Laboratory, and
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- Grzegorz Rymkiewicz
- Department of Pathology, The Maria Skłodowska-Curie Memorial Institute and Oncology Centre, Warsaw, Poland;
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- Wolfram Klapper
- Department of Pathology, Hematopathology Section and Lymph Node Registry, Christian Albrechts University, Kiel, Germany;
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- Elena M. Hartmann
- Institute of Pathology, University of Würzburg, Würzburg, Germany;
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- Pierre Sujobert
- Henri Mondor Hospital, Creteil, France;
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- Iwona Wlodarska
- Center for Human Genetics, KU Leuven, Leuven, Belgium;
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- Judith A. Ferry
- Department of Pathology, Massachusetts General Hospital, Boston, MA;
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- Philippe Gaulard
- Henri Mondor Hospital, Creteil, France;
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- German Ott
- Department of Clinical Pathology, Robert-Bosch-Krankenhaus, and Dr Margarete Fischer-Bosch Institute of Clinical Pharmacology, Stuttgart, Germany;
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- Andreas Rosenwald
- Institute of Pathology, University of Würzburg, Würzburg, Germany;
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- Armando Lopez-Guillermo
- Department of Hematology, Hematopathology Unit, Hospital Clínic, Barcelona, Spain; and
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- Leticia Quintanilla-Martinez
- Institute of Pathology, Eberhard-Karls-University of Tübingen, Tübingen, Germany
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- Nancy L. Harris
- Department of Pathology, Massachusetts General Hospital, Boston, MA;
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- Elaine S. Jaffe
- Laboratory of Pathology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD;
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- Reiner Siebert
- Institute of Human Genetics, University Hospital Schleswig-Holstein Campus Kiel/Christian-Albrechts University, Kiel, Germany;
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- Elias Campo
- Department of Pathology, Hematopathology Unit, Hospital Clínic, Institut d'Investigacions Biomèdiques August Pi i Sunyer, University of Barcelona, Barcelona, Spain;
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- Sílvia Beà
- Department of Pathology, Hematopathology Unit, Hospital Clínic, Institut d'Investigacions Biomèdiques August Pi i Sunyer, University of Barcelona, Barcelona, Spain;
Description
<jats:title>Key Points</jats:title> <jats:p>This report describes a multidisciplinary study characterizing the largest series of cyclin D1− MCL patients. CCND2 translocations are the most frequent genetic event (55%) in cyclin D1− MCL.</jats:p>
Journal
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- Blood
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Blood 121 (8), 1394-1402, 2013-02-21
American Society of Hematology
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Details 詳細情報について
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- CRID
- 1362544421409692032
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- ISSN
- 15280020
- 00064971
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- Data Source
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- Crossref
