Antibacterial Action of Curcumin against<i> Staphylococcus aureus</i>: A Brief Review

DOI PDF XML 被引用文献2件
  • Sin-Yeang Teow
    Sunway Institute for Healthcare Development (SIHD), Sunway University, 47500 Bandar Sunway, Selangor Darul Ehsan, Malaysia
  • Kitson Liew
    Molecular Pathology Unit, Cancer Research Centre (CaRC), Institute for Medical Research (IMR), 50588 Jalan Pahang, Kuala Lumpur, Malaysia
  • Syed A. Ali
    Advanced Medical and Dental Institute (AMDI), Universiti Sains Malaysia (USM), 13200 Kepala Batas, Pulau Pinang, Malaysia
  • Alan Soo-Beng Khoo
    Molecular Pathology Unit, Cancer Research Centre (CaRC), Institute for Medical Research (IMR), 50588 Jalan Pahang, Kuala Lumpur, Malaysia
  • Suat-Cheng Peh
    Sunway Institute for Healthcare Development (SIHD), Sunway University, 47500 Bandar Sunway, Selangor Darul Ehsan, Malaysia

書誌事項

公開日
2016
権利情報
  • http://creativecommons.org/licenses/by/4.0/
DOI
  • 10.1155/2016/2853045
公開者
Wiley

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説明

<jats:p>Curcumin, the major constituent of<jats:italic> Curcuma longa</jats:italic> L. (Zingiberaceae family) or turmeric, commonly used for cooking in Asian cuisine, is known to possess a broad range of pharmacological properties at relatively nontoxic doses. Curcumin is found to be effective against<jats:italic> Staphylococcus aureus</jats:italic> (<jats:italic>S. aureus</jats:italic>). As demonstrated by<jats:italic> in vitro</jats:italic> experiment, curcumin exerts even more potent effects when used in combination with various other antibacterial agents. Hence, curcumin which is a natural product derived from plant is believed to have profound medicinal benefits and could be potentially developed into a naturally derived antibiotic in the future. However, there are several noteworthy challenges in the development of curcumin as a medicine.<jats:italic> S. aureus</jats:italic> infections, particularly those caused by the multidrug-resistant strains, have emerged as a global health issue and urgent action is needed. This review focuses on the antibacterial activities of curcumin against both methicillin-sensitive<jats:italic> S. aureus</jats:italic> (MSSA) and methicillin-resistant<jats:italic> S. aureus</jats:italic> (MRSA). We also attempt to highlight the potential challenges in the effort of developing curcumin into a therapeutic antibacterial agent.</jats:p>

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