Complement C3 deficiency protects against neurodegeneration in aged plaque-rich APP/PS1 mice

DOI Web Site 被引用文献6件

Qiaoqiao Shi

Ann Romney Center for Neurologic Diseases, Brigham and Women’s Hospital, Building for Transformative Medicine, 9th Floor, 60 Fenwood Road, Boston, MA 02115, USA.
Saba Chowdhury

Ann Romney Center for Neurologic Diseases, Brigham and Women’s Hospital, Building for Transformative Medicine, 9th Floor, 60 Fenwood Road, Boston, MA 02115, USA.
Rong Ma

Ann Romney Center for Neurologic Diseases, Brigham and Women’s Hospital, Building for Transformative Medicine, 9th Floor, 60 Fenwood Road, Boston, MA 02115, USA.
Kevin X. Le

Ann Romney Center for Neurologic Diseases, Brigham and Women’s Hospital, Building for Transformative Medicine, 9th Floor, 60 Fenwood Road, Boston, MA 02115, USA.
Soyon Hong

Harvard Medical School, Boston, MA 02115, USA.
Barbara J. Caldarone

Harvard Medical School, Boston, MA 02115, USA.
Beth Stevens

Harvard Medical School, Boston, MA 02115, USA.
Cynthia A. Lemere

Ann Romney Center for Neurologic Diseases, Brigham and Women’s Hospital, Building for Transformative Medicine, 9th Floor, 60 Fenwood Road, Boston, MA 02115, USA.

説明

<jats:p>C3 deficiency protects against hippocampal neurodegeneration and cognitive decline in aged APP/PS1 mice despite abundant Aβ plaques.</jats:p>

Science Translational Medicine

Science Translational Medicine 9 (392), eaaf6295-, 2017-05-31

American Association for the Advancement of Science (AAAS)