Observation of electric-field induced aggregation in crystallizing protein solutions by forward light scattering

  • Takashi Wakamatsu
    Department of Electrical and Electronics System Engineering, Ibaraki National College of Technology 1 , Hitachinaka, Ibaraki 312-8508, Japan
  • Susumu Toyoshima
    Department of Electrical Engineering, Fukushima National College of Technology 2 , Iwaki, Fukushima 970-8034, Japan
  • Hidehiko Shimizu
    Department of Electrical and Electronic Engineering, Niigata University 3 , Niigata 950-2181, Japan

書誌事項

公開日
2011-10-10
DOI
  • 10.1063/1.3648114
公開者
AIP Publishing

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説明

<jats:p>Protein aggregation has been observed in-situ in lysozyme solutions under an internal electric field using a forward light scattering technique. Light scattering at small forward angles revealed that the application of a low voltage to the protein solutions significantly promotes aggregate formation. The solutions required a specific amount of time exposed to an electric field before the solution had undergone sufficient protein aggregation. The in-situ results from forward light scattering allow the characterization of the process.</jats:p>

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