The kynurenine pathway and quinolinic acid: pivotal roles in HIV associated neurocognitive disorders

Apsara Kandanearatchi, Bruce J. Brew

doi:10.1111/j.1742-4658.2012.08500.x

The kynurenine pathway and quinolinic acid: pivotal roles in HIV associated neurocognitive disorders

DOI Web Site Web Site 被引用文献1件

書誌事項

公開日: 2012-03-27

権利情報

http://onlinelibrary.wiley.com/termsAndConditions#vor

DOI

10.1111/j.1742-4658.2012.08500.x

公開者: Wiley

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説明

<jats:p>This brief review will first consider HIV associated neurocognitive disorder followed by the current understanding of its neuropathogenesis. Against this background the role of the kynurenine pathway will be detailed. Evidence both direct and indirect will be discussed for involvement of the kynurenine pathway at each step in the neuropathogenesis of HIV associated neurocognitive disorder.</jats:p>