Self-assembly of helical ribbons

  • Yevgeniya V. Zastavker
    Department of Physics, Center for Materials Science and Engineering, and Materials Processing Center, Massachusetts Institute of Technology, Cambridge, MA 02139-4307; Department of Medicine, Brockton/West Roxbury Veterans Affairs Medical Center, West Roxbury, MA 02132; Brigham and Women’s Hospital, Harvard Medical School, Boston, MA 02115; and Naval Research Laboratory, Center for Bio/Molecular Science and Engineering, Washington, DC 20375-5348
  • Neer Asherie
    Department of Physics, Center for Materials Science and Engineering, and Materials Processing Center, Massachusetts Institute of Technology, Cambridge, MA 02139-4307; Department of Medicine, Brockton/West Roxbury Veterans Affairs Medical Center, West Roxbury, MA 02132; Brigham and Women’s Hospital, Harvard Medical School, Boston, MA 02115; and Naval Research Laboratory, Center for Bio/Molecular Science and Engineering, Washington, DC 20375-5348
  • Aleksey Lomakin
    Department of Physics, Center for Materials Science and Engineering, and Materials Processing Center, Massachusetts Institute of Technology, Cambridge, MA 02139-4307; Department of Medicine, Brockton/West Roxbury Veterans Affairs Medical Center, West Roxbury, MA 02132; Brigham and Women’s Hospital, Harvard Medical School, Boston, MA 02115; and Naval Research Laboratory, Center for Bio/Molecular Science and Engineering, Washington, DC 20375-5348
  • Jayanti Pande
    Department of Physics, Center for Materials Science and Engineering, and Materials Processing Center, Massachusetts Institute of Technology, Cambridge, MA 02139-4307; Department of Medicine, Brockton/West Roxbury Veterans Affairs Medical Center, West Roxbury, MA 02132; Brigham and Women’s Hospital, Harvard Medical School, Boston, MA 02115; and Naval Research Laboratory, Center for Bio/Molecular Science and Engineering, Washington, DC 20375-5348
  • Joanne M. Donovan
    Department of Physics, Center for Materials Science and Engineering, and Materials Processing Center, Massachusetts Institute of Technology, Cambridge, MA 02139-4307; Department of Medicine, Brockton/West Roxbury Veterans Affairs Medical Center, West Roxbury, MA 02132; Brigham and Women’s Hospital, Harvard Medical School, Boston, MA 02115; and Naval Research Laboratory, Center for Bio/Molecular Science and Engineering, Washington, DC 20375-5348
  • Joel M. Schnur
    Department of Physics, Center for Materials Science and Engineering, and Materials Processing Center, Massachusetts Institute of Technology, Cambridge, MA 02139-4307; Department of Medicine, Brockton/West Roxbury Veterans Affairs Medical Center, West Roxbury, MA 02132; Brigham and Women’s Hospital, Harvard Medical School, Boston, MA 02115; and Naval Research Laboratory, Center for Bio/Molecular Science and Engineering, Washington, DC 20375-5348
  • George B. Benedek
    Department of Physics, Center for Materials Science and Engineering, and Materials Processing Center, Massachusetts Institute of Technology, Cambridge, MA 02139-4307; Department of Medicine, Brockton/West Roxbury Veterans Affairs Medical Center, West Roxbury, MA 02132; Brigham and Women’s Hospital, Harvard Medical School, Boston, MA 02115; and Naval Research Laboratory, Center for Bio/Molecular Science and Engineering, Washington, DC 20375-5348

書誌事項

公開日
1999-07-06
DOI
  • 10.1073/pnas.96.14.7883
公開者
Proceedings of the National Academy of Sciences

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説明

<jats:p>The self-assembly of helical ribbons is examined in a variety of multicomponent enantiomerically pure systems that contain a bile salt or a nonionic detergent, a phosphatidylcholine or a fatty acid, and a steroid analog of cholesterol. In almost all systems, two different pitch types of helical ribbons are observed: high pitch, with a pitch angle of 54 ± 2°, and low pitch, with a pitch angle of 11 ± 2°. Although the majority of these helices are right-handed, a small proportion of left-handed helices is observed. Additionally, a third type of helical ribbon, with a pitch angle in the range 30–47°, is occasionally found. These experimental findings suggest that the helical ribbons are crystalline rather than liquid crystal in nature and also suggest that molecular chirality may not be the determining factor in helix formation. The large yields of helices produced will permit a systematic investigation of their individual kinetic evolution and their elastic moduli.</jats:p>

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