Russell Body Gastritis: An Unusual, Tumor-like Lesion of the Gastric Mucosa

  • Andreas Erbersdobler
    From the Department of Pathology, University Hospital Hamburg-Eppendorf, Hamburg, Germany (Drs Erbersdobler and Petri); and the Department of Internal Medicine, Albertinen Hospital, Hamburg, Germany (Dr Lock)
  • Susan Petri
    From the Department of Pathology, University Hospital Hamburg-Eppendorf, Hamburg, Germany (Drs Erbersdobler and Petri); and the Department of Internal Medicine, Albertinen Hospital, Hamburg, Germany (Dr Lock)
  • Guntram Lock
    From the Department of Pathology, University Hospital Hamburg-Eppendorf, Hamburg, Germany (Drs Erbersdobler and Petri); and the Department of Internal Medicine, Albertinen Hospital, Hamburg, Germany (Dr Lock)

書誌事項

公開日
2004-08
DOI
  • 10.5858/2004-128-915-rbgaut
公開者
Archives of Pathology and Laboratory Medicine

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説明

<jats:title>Abstract</jats:title> <jats:p> The case of an 80-year-old woman who presented with epigastric symptoms is reported. Upper gastrointestinal endoscopy displayed <jats:italic>Candida</jats:italic> esophagitis and a localized swelling of the fundic mucosa. Histologic examination of the gastric biopsy showed a distinctive accumulation of numerous uniform plasma cells filled with so-called Russell bodies. On low-power view, the lesion resembled a neoplastic process due to the marked expansion of the lamina propria with distension of fundic glands. However, immunohistochemistry confirmed a polyclonal pattern of the plasma cells. This unusual reactive lesion of the gastric mucosa has only rarely been described and has been termed <jats:italic>Russell body gastritis</jats:italic> . </jats:p>

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