miR-30 Family: A Promising Regulator in Development and Disease

  • Ling Mao
    Special Key Laboratory of Gene Detection & Therapy of Guizhou Province, Zunyi Medical College, Zunyi, Guizhou 563003, China
  • Shiming Liu
    Special Key Laboratory of Gene Detection & Therapy of Guizhou Province, Zunyi Medical College, Zunyi, Guizhou 563003, China
  • Lin Hu
    Special Key Laboratory of Gene Detection & Therapy of Guizhou Province, Zunyi Medical College, Zunyi, Guizhou 563003, China
  • Li Jia
    Special Key Laboratory of Gene Detection & Therapy of Guizhou Province, Zunyi Medical College, Zunyi, Guizhou 563003, China
  • Hairong Wang
    Special Key Laboratory of Gene Detection & Therapy of Guizhou Province, Zunyi Medical College, Zunyi, Guizhou 563003, China
  • Mengmeng Guo
    Special Key Laboratory of Gene Detection & Therapy of Guizhou Province, Zunyi Medical College, Zunyi, Guizhou 563003, China
  • Chao Chen
    Special Key Laboratory of Gene Detection & Therapy of Guizhou Province, Zunyi Medical College, Zunyi, Guizhou 563003, China
  • Yun Liu
    Guizhou Provincial College-Based Key Lab for Tumor Prevention and Treatment with Distinctive Medicines, Zunyi Medical College, Zunyi, Guizhou 563003, China
  • Lin Xu
    Special Key Laboratory of Gene Detection & Therapy of Guizhou Province, Zunyi Medical College, Zunyi, Guizhou 563003, China

書誌事項

公開日
2018-05-29
権利情報
  • http://creativecommons.org/licenses/by/4.0/
DOI
  • 10.1155/2018/9623412
公開者
Wiley

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説明

<jats:p>MicroRNAs (miRNAs) are small noncoding RNAs that negatively regulate posttranscriptional expression of target genes. Accumulating evidences have demonstrated that the miR-30 family, as a member of microRNAs, played a crucial regulating role in the development of tissues and organs and the pathogenesis of clinical diseases, which indicated that it may be a promising regulator in development and disease. This review aims to clarify the current progress on the regulating role of miR-30 family in tissues and organs development and related disease and highlight their research prospective in the future.</jats:p>

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