Microfluidic tectonics: A comprehensive construction platform for microfluidic systems

  • David J. Beebe
    The Beckman Institute for Advanced Science and Technology, University of Illinois at Urbana–Champaign, Urbana, IL 61801; and Department of Biomedical Engineering, University of Wisconsin, Madison, WI 53706
  • Jeffrey S. Moore
    The Beckman Institute for Advanced Science and Technology, University of Illinois at Urbana–Champaign, Urbana, IL 61801; and Department of Biomedical Engineering, University of Wisconsin, Madison, WI 53706
  • Qing Yu
    The Beckman Institute for Advanced Science and Technology, University of Illinois at Urbana–Champaign, Urbana, IL 61801; and Department of Biomedical Engineering, University of Wisconsin, Madison, WI 53706
  • Robin H. Liu
    The Beckman Institute for Advanced Science and Technology, University of Illinois at Urbana–Champaign, Urbana, IL 61801; and Department of Biomedical Engineering, University of Wisconsin, Madison, WI 53706
  • Mary L. Kraft
    The Beckman Institute for Advanced Science and Technology, University of Illinois at Urbana–Champaign, Urbana, IL 61801; and Department of Biomedical Engineering, University of Wisconsin, Madison, WI 53706
  • Byung-Ho Jo
    The Beckman Institute for Advanced Science and Technology, University of Illinois at Urbana–Champaign, Urbana, IL 61801; and Department of Biomedical Engineering, University of Wisconsin, Madison, WI 53706
  • Chelladurai Devadoss
    The Beckman Institute for Advanced Science and Technology, University of Illinois at Urbana–Champaign, Urbana, IL 61801; and Department of Biomedical Engineering, University of Wisconsin, Madison, WI 53706

Description

<jats:p>A microfluidic platform for the construction of microscale components and autonomous systems is presented. The platform combines liquid-phase photopolymerization, lithography, and laminar flow to allow the creation of complex and autonomous microfluidic systems. The fabrication of channels, actuators, valves, sensors, and systems is demonstrated. Construction times can be as short as 10 min, providing ultrarapid prototyping of microfluidic systems.</jats:p>

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