書誌事項
- 公開日
- 2015-06-09
- 権利情報
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- http://onlinelibrary.wiley.com/termsAndConditions#vor
- DOI
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- 10.1016/j.febslet.2015.05.054
- 公開者
- Wiley
この論文をさがす
説明
<jats:p>Metabolic homeostasis in the organism is assured both by the nervous system and by hormones. Among a plethora of hormones regulating metabolism, serotonin presents a number of unique features. Unlike classical hormones serotonin is produced in different anatomical locations. In brain it acts as a neurotransmitter and in the periphery it can act as a hormone, auto‐ and/or paracrine factor, or intracellular signaling molecule. Serotonin does not cross the blood–brain barrier; therefore the two major pools of this bioamine remain separated. Although 95% of serotonin is produced in the periphery, its functions have been ignored until recently. Here we review the impact of the peripheral serotonin on the regulation of function of the organs involved in glucose and lipid homeostasis.</jats:p>
収録刊行物
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- FEBS Letters
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FEBS Letters 589 (15), 1728-1734, 2015-06-09
Wiley