GABA in the Mammalian Enteric Nervous System

  • Anthony Krantis
    A. Krantis is a Professor in the Department of Cellular and Molecular Medicine, Digestive Diseases Research Group, University of Ottawa, Ottawa, ON, Canada K1H 8M5.

書誌事項

公開日
2000-12
DOI
  • 10.1152/physiologyonline.2000.15.6.284
公開者
American Physiological Society

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説明

<jats:p>γ-Aminobutyric acid (GABA) is a transmitter of enteric interneurons, targeting excitatory GABA<jats:sub>A</jats:sub>or inhibitory GABA<jats:sub>B</jats:sub>receptors that modulate motility and mucosal function. Enteric GABA may also subserve hormonal and paracrine signaling. Disruption in gastrointestinal function following perturbation of enteric GABA receptors presents potential new target sites for drug development.</jats:p>

収録刊行物

  • Physiology

    Physiology 15 (6), 284-290, 2000-12

    American Physiological Society

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