Oral immunotherapy for food allergy: mechanisms and role in management
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- A. Nowak‐Węgrzyn
- Pediatric Allergy and Immunology Jaffe Food Allergy Institute Icahn School of Medicine at Mount Sinai Kravis Children's Hospital New York NY USA
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- S. Albin
- Pediatric Allergy and Immunology Jaffe Food Allergy Institute Icahn School of Medicine at Mount Sinai Kravis Children's Hospital New York NY USA
書誌事項
- 公開日
- 2015-01-27
- 権利情報
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- http://onlinelibrary.wiley.com/termsAndConditions#vor
- DOI
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- 10.1111/cea.12382
- 公開者
- Wiley
この論文をさがす
説明
<jats:title>Summary</jats:title><jats:p>With the emergence of food allergy as an important public health problem, it has become clear that there is an unmet need in regard to treatment. In particular, <jats:styled-content style="fixed-case">I</jats:styled-content>g<jats:styled-content style="fixed-case">E</jats:styled-content>‐mediated food allergy that is associated with risk of fatal anaphylaxis has been the subject of multiple studies in the past decade. The growing body of evidence derived from multiple centres and various study designs indicates that for <jats:styled-content style="fixed-case">I</jats:styled-content>g<jats:styled-content style="fixed-case">E</jats:styled-content>‐mediated food allergy, immunomodulation through food immunotherapy is possible; however, the extent of protection afforded by such treatment is highly variable. At this time, the capacity for food immunotherapy to restore permanent tolerance to food has not been demonstrated conclusively. This review will discuss these topics as they apply to the most important studies of food oral immunotherapy.</jats:p>
収録刊行物
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- Clinical & Experimental Allergy
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Clinical & Experimental Allergy 45 (2), 368-383, 2015-01-27
Wiley