Asymmetric organocatalytic decarboxylative Mannich reaction using β-keto acids: A new protocol for the synthesis of chiral β-amino ketones
Description
<jats:p>The first decarboxylative Mannich reaction employing β-keto acids, catalyzed by cinchonine-derived bifunctional thiourea catalyst has been described. The desired β-amino ketones were obtained in excellent yields and with moderate to good enantioselectivities.</jats:p>
Journal
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- Beilstein Journal of Organic Chemistry
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Beilstein Journal of Organic Chemistry 8 1279-1283, 2012-08-13
Beilstein Institut
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Details 詳細情報について
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- CRID
- 1362825894725943424
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- ISSN
- 18605397
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- Data Source
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- Crossref