The current potential of high‐intensity focused ultrasound for pancreatic carcinoma

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  • Atsushi Sofuni
    Department of Gastroenterology and Hepatology Tokyo Medical University 6‐7‐1 Nishishinjuku, Shinjuku‐ku Tokyo 160‐0023 Japan
  • Fuminori Moriyasu
    Department of Gastroenterology and Hepatology Tokyo Medical University 6‐7‐1 Nishishinjuku, Shinjuku‐ku Tokyo 160‐0023 Japan
  • Takatomo Sano
    Department of Gastroenterology and Hepatology Tokyo Medical University 6‐7‐1 Nishishinjuku, Shinjuku‐ku Tokyo 160‐0023 Japan
  • Kota Yamada
    Department of Gastroenterology and Hepatology Tokyo Medical University 6‐7‐1 Nishishinjuku, Shinjuku‐ku Tokyo 160‐0023 Japan
  • Fumihide Itokawa
    Department of Gastroenterology and Hepatology Tokyo Medical University 6‐7‐1 Nishishinjuku, Shinjuku‐ku Tokyo 160‐0023 Japan
  • Takayoshi Tsuchiya
    Department of Gastroenterology and Hepatology Tokyo Medical University 6‐7‐1 Nishishinjuku, Shinjuku‐ku Tokyo 160‐0023 Japan
  • Shujiro Tsuji
    Department of Gastroenterology and Hepatology Tokyo Medical University 6‐7‐1 Nishishinjuku, Shinjuku‐ku Tokyo 160‐0023 Japan
  • Toshio Kurihara
    Department of Gastroenterology and Hepatology Tokyo Medical University 6‐7‐1 Nishishinjuku, Shinjuku‐ku Tokyo 160‐0023 Japan
  • Kentaro Ishii
    Department of Gastroenterology and Hepatology Tokyo Medical University 6‐7‐1 Nishishinjuku, Shinjuku‐ku Tokyo 160‐0023 Japan
  • Takao Itoi
    Department of Gastroenterology and Hepatology Tokyo Medical University 6‐7‐1 Nishishinjuku, Shinjuku‐ku Tokyo 160‐0023 Japan

書誌事項

公開日
2011-03-02
権利情報
  • http://onlinelibrary.wiley.com/termsAndConditions#vor
DOI
  • 10.1007/s00534-010-0355-4
公開者
Wiley

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<jats:title>Abstract</jats:title><jats:sec><jats:title>Introduction</jats:title><jats:p>Pancreatic carcinoma has one of the poorest prognoses among malignant tumors. Many pancreatic carcinoma patients who undergo common treatments, such as surgery, radio‐chemotherapy and chemotherapy, gained little benefit because of the histological characteristics.</jats:p></jats:sec><jats:sec><jats:title>Materials and methods</jats:title><jats:p>HIFU is a new technique of noninvasive treatment for unresectable pancreatic carcinoma. HIFU has the ability to ablate the deep tissues inside body from an external source using high‐intensity focused ultrasound. The effects of HIFU can result in cell destruction and tissue necrosis.</jats:p></jats:sec><jats:sec><jats:title>Results</jats:title><jats:p>Results from study in China in 251 patients with advanced pancreatic carcinoma suggested that HIFU treatment could reduce the size of tumors without causing complications and prolong survival. Moreover, according to some reports from China, HIFU treatment is suggested to be useful as the one of palliative treatments for unresectable pancreatic carcinoma. Our case of HIFU therapy for pancreatic carcinoma is presented including pathological findings in this paper. The results suggested that HIFU treatment might be effective in controlling local tumor.</jats:p></jats:sec><jats:sec><jats:title>Conclusion</jats:title><jats:p>HIFU therapy may have the possibility of becoming one of the combination therapies for treating pancreatic carcinoma in the future.</jats:p></jats:sec>

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