THE REASON FOR THE SHAPE OF THE DISTENSIBILITY CURVES OF ARTERIES

DOI Web Site 被引用文献3件
  • Margot R. Roach
    Laboratory of Biophysics, University of Western Ontario, London, Ontario
  • Alan C. Burton
    Laboratory of Biophysics, University of Western Ontario, London, Ontario

書誌事項

公開日
1957-01-01
権利情報
  • http://www.nrcresearchpress.com/page/about/CorporateTextAndDataMining
DOI
  • 10.1139/y57-080
公開者
Canadian Science Publishing

この論文をさがす

説明

<jats:p> It is characteristic of arteries that they do not obey Hooke's law, but resist further stretch more strongly, the more they are stretched. It appears that this might be due to the combination of elastin fibers in the elastic laminae, with the much less distensible collagenous libers in the media and adventitia, more and more of which reach their 'unstretched length' as distension is increased. This has been verified on human iliac arteries, from autopsy, by comparing the 'elastic diagrams' (tension vs. circumference) before and after differential digestion of collagen by formic acid, and digestion of elastin by crude trypsin (containing an elastase). This proved that the resistance to stretch at low pressures was almost entirely due to elastin fibers, that at physiological pressures due to both collagenous and elastin fibers, but dominantly to collagen, and that at high pressures almost entirely due to collagenous fibers. In future work on the effect of age on the elasticity of iliac arteries, the initial slope of the elastic diagram can be taken as an index of the state, or number, of the elastin fibers, and the final slope as an index of the state, or number, of collagenous fibers. </jats:p>

収録刊行物

被引用文献 (3)*注記

もっと見る

詳細情報 詳細情報について

問題の指摘

ページトップへ