Changes in neurosyphilis presentation: a survey on 286 patients

DOI Web Site Web Site 被引用文献1件
  • F. Drago
    Di.S.Sal. Section of Dermatology IRCCS Azienda Ospedaliera Universitaria San Martino‐IST Genoa Italy
  • G. Merlo
    Di.S.Sal. Section of Dermatology IRCCS Azienda Ospedaliera Universitaria San Martino‐IST Genoa Italy
  • G. Ciccarese
    Di.S.Sal. Section of Dermatology IRCCS Azienda Ospedaliera Universitaria San Martino‐IST Genoa Italy
  • A.F. Agnoletti
    Di.S.Sal. Section of Dermatology IRCCS Azienda Ospedaliera Universitaria San Martino‐IST Genoa Italy
  • E. Cozzani
    Di.S.Sal. Section of Dermatology IRCCS Azienda Ospedaliera Universitaria San Martino‐IST Genoa Italy
  • A. Rebora
    Di.S.Sal. Section of Dermatology IRCCS Azienda Ospedaliera Universitaria San Martino‐IST Genoa Italy
  • A. Parodi
    Di.S.Sal. Section of Dermatology IRCCS Azienda Ospedaliera Universitaria San Martino‐IST Genoa Italy

書誌事項

公開日
2016-06-15
権利情報
  • http://onlinelibrary.wiley.com/termsAndConditions#vor
DOI
  • 10.1111/jdv.13753
公開者
Wiley

この論文をさがす

説明

<jats:title>Abstract</jats:title><jats:p>Although neurosyphilis (<jats:styled-content style="fixed-case">NS</jats:styled-content>) keeps plaguing worldwide, often with oligosymptomatic and atypical manifestations, the most recent reports fail to provide useful information, like details of the clinical history and even of the previous early therapy. We conducted a survey of the literature of the last 5 years on the clinical presentation of <jats:styled-content style="fixed-case">NS</jats:styled-content>, recording the aforementioned inaccuracies. One hundred and thirty‐seven articles were collected, reporting on 286 patients. General paresis was the commonest form (49%), often manifesting with cognitive impairment and psychiatric symptoms. Syphilitic meningitis was found in 63 patients (22%), mainly with ocular or auditory involvement. Meningovascular and tabetic form were both found in 12% of cases. Gummatous and epileptic manifestations were rare. Perusal of the literature confirms that <jats:styled-content style="fixed-case">NS</jats:styled-content> prevalence is increasing, often with manifestations that are atypical for timing and type of lesions. Unfortunately, many articles are lacking of critical information, like an accurate clinical history and timing of the therapy making difficult to assess the effectiveness of penicillin in preventing <jats:styled-content style="fixed-case">NS</jats:styled-content>.</jats:p>

収録刊行物

被引用文献 (1)*注記

もっと見る

詳細情報 詳細情報について

問題の指摘

ページトップへ