書誌事項
- タイトル別名
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- Relationship to formaldehyde allergy
- 公開日
- 1988-04
- 権利情報
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- http://onlinelibrary.wiley.com/termsAndConditions#vor
- DOI
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- 10.1111/j.1600-0536.1988.tb02802.x
- 公開者
- Wiley
この論文をさがす
説明
<jats:p>The relationship between contact allergy to formaldehyde and positive patch test reactions to DMDM hydantoin was investigated– 35 formaldehyde‐allergic patients were patch tested with serial dilutions of formaldehyde (0.1% 0.3% 1.0% aq.) and DM hydantoin (the non‐formaldehyde‐containing parent compound of DMDM hydantoin), 21 were also patch tested with MDM hydantoin (1 molecule formaldehyde) in serial dilutions: 7 (33%) reacted to 1 or more concentrations. The other 14 were also tested with DMDM hydantoin (2 molecules formaldehyde) in serial dilutions: 8 (57%) reacted to 1 or more concentrations. Patients patch‐test‐positive to formaldehyde 0.1% and. or 0.3% tended to show more patch test reactivity to (D)MDM hydantoin than those who resided only to 1%. Aqueous solutions of (D)MDM hydantoin in concentrations as used in cosmetic products therefore contain enough fret formaldehyde to cause dermatitis in a patch lost system in some formaldehyde‐allergic patients: 12 such patients applied a cream containing 1% DMDM hydantoin to the flexor aspect of the lower arm twice daily for 1 week; 4 (33%) developed dermatitis. The use of a cream containing 0.25% DMDM hydantoin in these 4 patients still caused dermatitis in I and provoked itching in another. An increase in the use of DMDM hydantoin in cosmetic products will also inevitable increase the risk of cosmetic dermatitis in consumers allergic to formaldehyde.</jats:p>
収録刊行物
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- Contact Dermatitis
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Contact Dermatitis 18 (4), 197-201, 1988-04
Wiley