Treatment of allergic rhinitis using mobile technology with real‐world data: The <scp>MASK</scp> observational pilot study
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- J. Bousquet
- Contre les MAladies Chroniques Pour un VIeillissement Actif en France European Innovation Partnership on Active and Healthy Ageing Reference Site MACVIA‐France Montpellier France
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- P. Devillier
- Laboratoire de Pharmacologie Respiratoire UPRES EA220 Pôle des Maladies Respiratoires Hôpital Foch Suresnes ‐ Université Versailles Saint‐Quentin Versailles France
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- S. Arnavielhe
- Kyomed Montpellier France
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- A. Bedbrook
- Contre les MAladies Chroniques Pour un VIeillissement Actif en France European Innovation Partnership on Active and Healthy Ageing Reference Site MACVIA‐France Montpellier France
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- G. Alexis‐Alexandre
- EZY Montpellier France
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- M. van Eerd
- Peercode BV Gerdermalsen The Netherlands
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- R. Murray
- Medical Communications Consultant MedScript Ltd Dundalk Ireland
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- G. W. Canonica
- Allergy and Respiratory Diseases Department of Internal Medicine IRCCS San Martino‐IST‐University of Genoa Genoa Italy
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- M. Illario
- Division for Health Innovation Campania Region and Federico II University Hospital Naples (R&D and DISMET) Naples Italy
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- E. Menditto
- Center of Pharmacoeconomics CIRFF University of Naples Federico II Naples Italy
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- G. Passalacqua
- Allergy and Respiratory Diseases Department of Internal Medicine IRCCS San Martino‐IST‐University of Genoa Genoa Italy
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- C. Stellato
- Department of Medicine, Surgery and Dentistry “Scuola Medica Salernitana” University of Salerno Salerno Italy
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- M. Triggiani
- Department of Medicine, Surgery and Dentistry “Scuola Medica Salernitana” University of Salerno Salerno Italy
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- P. Carreiro‐Martins
- Servicio de Imunoalergologia EPE – Nova Medical School Respiratory Research Group CEDOC Centro Hospitalar de Lisboa Central Lisbon Portugal
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- J. Fonseca
- Faculdade de Medicina Center for Health Technology and Services Research‐CINTESIS Universidade do Porto Porto Portugal
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- M. Morais Almeida
- Rhinology Unit & Smell Clinic ENT Department Hospital Clinic Clinical & Experimental Respiratory Immunoallergy, IDIBAPS, CIBERES University of Barcelona Barcelona Spain
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- L. Nogueira‐Silva
- Department of Internal Medicine Center for Health Technology and Services Research—CINTESIS Centro Hospitalar Sao Joao Porto Portugal
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- A. M. Pereira
- Allergy Unit CUF Porto Instituto & Hospital Porto Portugal
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- A. Todo Bom
- Imunoalergologia Centro Hospitalar Universitario de Coimbra Faculty of Medicine University of Coimbra Coimbra Portugal
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- I. Bosse
- Allergist La Rochelle France
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- D. Caimmi
- CHU de Montpellier UPMC, Paris 06 UMR‐S 1136, IPLESP, Equipe EPAR Sorbonne Universités Paris France
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- P. Demoly
- CHU de Montpellier UPMC, Paris 06 UMR‐S 1136, IPLESP, Equipe EPAR Sorbonne Universités Paris France
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- J. F. Fontaine
- Allergist Reims France
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- J. Just
- Allergology Department Centre de l'Asthme et des Allergies Hôpital d'Enfants Armand‐Trousseau – INSERM UMRS 1136, UPMC Univ Paris 06 – Institut Pierre Louis d'Epidémiologie et de Santé Publique Equipe EPAR Sorbonne Universités Paris France
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- G. L. Onorato
- Contre les MAladies Chroniques Pour un VIeillissement Actif en France European Innovation Partnership on Active and Healthy Ageing Reference Site MACVIA‐France Montpellier France
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- M. L. Kowalski
- Department of Immunology, Rheumatology and Allergy Medical University of Lodz Lodz Poland
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- P. Kuna
- Division of Internal Medicine Asthma and Allergy Barlicki University Hospital Medical University of Lodz Lodz Poland
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- B. Samolinski
- Department of Prevention of Environmental Hazards and Allergology Medical University of Warsaw Warsaw Poland
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- J. M. Anto
- ISGLoBAL Centre for Research in Environmental Epidemiology (CREAL) Barcelona Spain
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- J. Mullol
- Rhinology Unit & Smell Clinic ENT Department Hospital Clinic Clinical & Experimental Respiratory Immunoallergy, IDIBAPS, CIBERES University of Barcelona Barcelona Spain
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- A. Valero
- Pneumology and Allergy Department Hospital Clınic Clinical & Experimental Respiratory Immunoallergy IDIBAPS, CIBERES University of Barcelona Barcelona Spain
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- P. V. Tomazic
- Department of ENT Medical University of Graz Graz Austria
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- K. C. Bergmann
- Comprehensive Allergy‐Centre‐Charité Department of Dermatology and Allergy Global Allergy and Asthma European Network (GA<sup>2</sup>LEN) Charité Universitatsmedizin Berlin Berlin Germany
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- T. Keil
- Institute of Social Medicine, Epidemiology and Health Economics Charité—Universitatsmedizin Berlin Germany
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- L. Klimek
- Center for Rhinology and Allergology Wiesbaden Germany
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- R. Mösges
- Institute of Medical Statistics and Computational Biology Medical Faculty University of Cologne Cologne Germany
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- S. Shamai
- Institute of Medical Statistics and Computational Biology Medical Faculty University of Cologne Cologne Germany
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- T. Zuberbier
- Comprehensive Allergy‐Centre‐Charité Department of Dermatology and Allergy Global Allergy and Asthma European Network (GA<sup>2</sup>LEN) Charité Universitatsmedizin Berlin Berlin Germany
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- E. Murphy
- Newcastle OHS The Newcastle upon Tyne NHS Foundation Hospitals Trust Newcastle upon Tyne UK
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- P. McDowall
- Newcastle OHS The Newcastle upon Tyne NHS Foundation Hospitals Trust Newcastle upon Tyne UK
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- D. Price
- Observational and Pragmatic Research Institute Singapore City Singapore
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- D. Ryan
- Allergy and Respiratory Research Group Usher Institute of Population Health Sciences and Informatics University of Edinburgh Edinburgh UK
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- A. Sheikh
- Asthma UK Centre for Applied Research Centre of Medical Informatics Usher Institute of Population Health Sciences and Informatics The University of Edinburgh Edinburgh UK
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- N. H. Chavannes
- Department of Public Health and Primary Care Leiden University Medical Center Leiden The Netherlands
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- W. J. Fokkens
- Department of Otorhinolaryngology Academic Medical Centre Amsterdam The Netherlands
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- V. Kvedariene
- Clinic of Infectious, Chest Diseases, Dermatology and Allergology Vilnius University Vilnius Lithuania
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- A. Valiulis
- Vilnius University Clinic of Children's Diseases and Public Health Institute Vilnius Lithuania
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- C. Bachert
- ENT Department Upper Airways Research Laboratory Ghent University Hospital Ghent Belgium
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- P. W. Hellings
- Euforea Brussels Belgium
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- I. Kull
- Department of Clinical Science and Education Sodersjukhuset Karolinska Institutet Stockholm Sweden
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- E. Melen
- Department of Clinical Science and Education Sodersjukhuset Karolinska Institutet Stockholm Sweden
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- M. Wickman
- Sodersjukhuset Sachs' Children and Youth Hospital Stockholm Sweden
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- C. Bindslev‐Jensen
- Department of Dermatology and Allergy Centre Odense Research Center for Anaphylaxis (ORCA) Odense University Hospital Odense Denmark
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- E. Eller
- Department of Dermatology and Allergy Centre Odense Research Center for Anaphylaxis (ORCA) Odense University Hospital Odense Denmark
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- T. Haahtela
- Skin and Allergy Hospital Helsinki University Hospital Helsinki Finland
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- N. G. Papadopoulos
- Center for Pediatrics and Child Health Institute of Human Development Royal Manchester Children's Hospital University of Manchester Manchester UK
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- I. Annesi‐Maesano
- EPAR U707 INSERM Paris France
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- M. Bewick
- i Q4U Consultants Ltd London UK
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- S. Bosnic‐Anticevich
- Woolcock Institute of Medical Research University of Sydney Sydney NSW Australia
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- A. A. Cruz
- ProAR—Nucleo de Excelencia em Asma Federal University of Bahia Salvador Brazil
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- G. De Vries
- Peercode BV Gerdermalsen The Netherlands
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- B. Gemicioglu
- Department of Pulmonary Diseases Cerrahpasa Faculty of Medicine Istanbul University Istanbul Turkey
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- D. Larenas‐Linnemann
- Center of Excellence in Asthma and Allergy Hospital Médica Sur Mexico City Mexico
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- D. Laune
- Kyomed Montpellier France
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- E. Mathieu‐Dupas
- Kyomed Montpellier France
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- R. E. O'Hehir
- Department of Allergy, Immunology and Respiratory Medicine Alfred Hospital and Central Clinical School Monash University Melbourne Vic. Australia
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- O. Pfaar
- Center for Rhinology and Allergology Wiesbaden Germany
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- F. Portejoie
- Contre les MAladies Chroniques Pour un VIeillissement Actif en France European Innovation Partnership on Active and Healthy Ageing Reference Site MACVIA‐France Montpellier France
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- V. Siroux
- INSERM Universite Grenoble Alpes IAB U 1209 Team of Environmental Epidemiology Applied to Reproduction and Respiratory Health Université Joseph Fourier Grenoble France
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- O. Spranger
- Global Allergy and Asthma Platform GAAPP Vienna Austria
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- E. Valovirta
- Department of Lung Diseases and Clinical Allergology Terveystalo Allergy Clinic University of Turku Turku Finland
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- O. VandenPlas
- Department of Chest Medicine Centre Hospitalier Universitaire UCL Namur Université Catholique de Louvain Yvoir Belgium
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- A. Yorgancioglu
- Department of Pulmonology Celal Bayar University Manisa Turkey
Abstract
<jats:title>Abstract</jats:title><jats:sec><jats:title>Background</jats:title><jats:p>Large observational implementation studies are needed to triangulate the findings from randomized control trials as they reflect “real‐world” everyday practice. In a pilot study, we attempted to provide additional and complementary insights on the real‐life treatment of allergic rhinitis (AR) using mobile technology.</jats:p></jats:sec><jats:sec><jats:title>Methods</jats:title><jats:p>A mobile phone app (<jats:italic>Allergy Diary</jats:italic>, freely available in Google Play and Apple App stores) collects the data of daily visual analog scales (<jats:styled-content style="fixed-case">VAS</jats:styled-content>) for (i) overall allergic symptoms, (ii) nasal, ocular, and asthma symptoms, (iii) work, as well as (iv) medication use using a treatment scroll list including all medications (prescribed and over the counter (<jats:styled-content style="fixed-case">OTC</jats:styled-content>)) for rhinitis customized for 15 countries.</jats:p></jats:sec><jats:sec><jats:title>Results</jats:title><jats:p>A total of 2871 users filled in 17 091 days of <jats:styled-content style="fixed-case">VAS</jats:styled-content> in 2015 and 2016. Medications were reported for 9634 days. The assessment of days appeared to be more informative than the course of the treatment as, in real life, patients do not necessarily use treatment on a daily basis; rather, they appear to increase treatment use with the loss of symptom control. The <jats:italic>Allergy Diary</jats:italic> allowed differentiation between treatments within or between classes (intranasal corticosteroid use containing medications and oral H1‐antihistamines). The control of days differed between no [best control], single, or multiple treatments (worst control).</jats:p></jats:sec><jats:sec><jats:title>Conclusions</jats:title><jats:p>This study confirms the usefulness of the <jats:italic>Allergy Diary</jats:italic> in accessing and assessing everyday use and practice in AR. This pilot observational study uses a very simple assessment (<jats:styled-content style="fixed-case">VAS</jats:styled-content>) on a mobile phone, shows novel findings, and generates new hypotheses.</jats:p></jats:sec>
Journal
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- Allergy
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Allergy 73 (9), 1763-1774, 2018-03-22
Wiley
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Details 詳細情報について
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- CRID
- 1362825895875316736
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- ISSN
- 13989995
- 01054538
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- Data Source
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- Crossref