F1-ATPase Is a Highly Efficient Molecular Motor that Rotates with Discrete 120° Steps

書誌事項

公開日
1998-06
権利情報
  • https://www.elsevier.com/tdm/userlicense/1.0/
  • https://www.elsevier.com/legal/tdmrep-license
  • http://www.elsevier.com/open-access/userlicense/1.0/
DOI
  • 10.1016/s0092-8674(00)81456-7
公開者
Elsevier BV

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説明

A single molecule of F1-ATPase, a portion of ATP synthase, is by itself a rotary motor in which a central gamma subunit rotates against a surrounding cylinder made of alpha3beta3 subunits. Driven by three catalytic betas, each fueled with ATP, gamma makes discrete 120 degree steps, occasionally stepping backward. The work done in each step is constant over a broad range of imposed load and is close to the free energy of hydrolysis of one ATP molecule.

収録刊行物

  • Cell

    Cell 93 (7), 1117-1124, 1998-06

    Elsevier BV

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