Breaking free from vascular confinement: status and prospects for submicron ultrasound contrast agents
-
- Carly Pellow
- Department of Medical Biophysics University of Toronto Toronto Canada
-
- David E. Goertz
- Department of Medical Biophysics University of Toronto Toronto Canada
-
- Gang Zheng
- Department of Medical Biophysics University of Toronto Toronto Canada
書誌事項
- 公開日
- 2017-11-17
- 権利情報
-
- http://onlinelibrary.wiley.com/termsAndConditions#vor
- DOI
-
- 10.1002/wnan.1502
- 公開者
- Wiley
この論文をさがす
説明
<jats:p>The development of encapsulated microbubbles (~1–6 μm) has expanded the utility of ultrasound from soft tissue anatomical imaging to not only functional intravascular imaging, but therapeutic interventions, with compelling studies of elicited biological effects. The large diameter of these bubbles has confined their utility to the vasculature, but converging interdisciplinary research pathways are giving rise to new submicron ultrasound contrast agents capable of extending their effects beyond the vascular compartment. This article reviews the status and prospects of exogenous agents including nanobubbles, echogenic liposomes, gas vesicles, cavitation seeds, and nanodroplets, and assesses outstanding criticisms preventing their advance.</jats:p><jats:p>This article is categorized under:<jats:list list-type="simple"><jats:list-item><jats:p>Diagnostic Tools > In Vivo Nanodiagnostics and Imaging</jats:p></jats:list-item><jats:list-item><jats:p>Therapeutic Approaches and Drug Discovery > Emerging Technologies</jats:p></jats:list-item></jats:list></jats:p>
収録刊行物
-
- WIREs Nanomedicine and Nanobiotechnology
-
WIREs Nanomedicine and Nanobiotechnology 10 (4), e1502-, 2017-11-17
Wiley