Disease and treatment characteristics do not predict symptom occurrence profiles in oncology outpatients receiving chemotherapy
-
- Christine Miaskowski
- Department of Physiological Nursing, School of Nursing University of California at San Francisco San Francisco California
-
- Bruce A. Cooper
- Department of Community Health Systems, School of Nursing University of California at San Francisco San Francisco California
-
- Michelle Melisko
- Department of Medicine, School of Medicine University of California at San Francisco San Francisco California
-
- Lee‐May Chen
- Department of Obstetrics and Gynecology, School of Medicine University of California at San Francisco San Francisco California
-
- Judy Mastick
- Department of Physiological Nursing, School of Nursing University of California at San Francisco San Francisco California
-
- Claudia West
- Department of Physiological Nursing, School of Nursing University of California at San Francisco San Francisco California
-
- Steven M. Paul
- Department of Physiological Nursing, School of Nursing University of California at San Francisco San Francisco California
-
- Laura B. Dunn
- Department of Psychiatry, School of Medicine University of California at San Francisco San Francisco California
-
- Brian L. Schmidt
- Department of Oral and Maxillofacial Surgery, School of Dentistry New York University New York New York
-
- Marilyn Hammer
- School of Nursing New York University New York New York
-
- Frances Cartwright
- School of Nursing New York University New York New York
-
- Fay Wright
- School of Nursing New York University New York New York
-
- Dale J. Langford
- Department of Physiological Nursing, School of Nursing University of California at San Francisco San Francisco California
-
- Kathryn Lee
- Department of Community Health Systems, School of Nursing University of California at San Francisco San Francisco California
-
- Bradley E. Aouizerat
- Department of Physiological Nursing, School of Nursing University of California at San Francisco San Francisco California
説明
<jats:sec><jats:title>BACKGROUND</jats:title><jats:p>A large amount of interindividual variability exists in the occurrence of symptoms in patients receiving chemotherapy (CTX). The purposes of the current study, which was performed in a sample of 582 oncology outpatients who were receiving CTX, were to identify subgroups of patients based on their distinct experiences with 25 commonly occurring symptoms and to identify demographic and clinical characteristics associated with subgroup membership. In addition, differences in quality of life outcomes were evaluated.</jats:p></jats:sec><jats:sec><jats:title>METHODS</jats:title><jats:p>Oncology outpatients with breast, gastrointestinal, gynecological, or lung cancer completed the Memorial Symptom Assessment Scale before their next cycle of CTX. Latent class analysis was used to identify subgroups of patients with distinct symptom experiences.</jats:p></jats:sec><jats:sec><jats:title>RESULTS</jats:title><jats:p>Three distinct subgroups of patients were identified (ie, 36.1% in Low class; 50.0% in Moderate class, and 13.9% in All High class). Patients in the All High class were significantly younger and more likely to be female and nonwhite, and had lower levels of social support, lower socioeconomic status, poorer functional status, and a higher level of comorbidity.</jats:p></jats:sec><jats:sec><jats:title>CONCLUSIONS</jats:title><jats:p>Findings from the current study support the clinical observation that some oncology patients experience a differentially higher symptom burden during CTX. These high‐risk patients experience significant decrements in quality of life. <jats:bold><jats:italic>Cancer</jats:italic> 2014;120:2371–2378</jats:bold>. © <jats:italic>2014 American Cancer Society</jats:italic>.</jats:p></jats:sec>
収録刊行物
-
- Cancer
-
Cancer 120 (15), 2371-2378, 2014-05-02
Wiley