Easily Accessible Auxiliary for Palladium‐Catalyzed Intramolecular Amination of C(sp<sup>2</sup>)H and C(sp<sup>3</sup>)H Bonds at δ‐ and ε‐Positions
説明
<jats:title>Abstract</jats:title><jats:p>An easily synthesized and accessible N,O‐bidentate auxiliary has been developed for selective CH activation under palladium catalysis. The novel auxiliary showed its first powerful application in CH functionalization of remote positions. Both C(sp<jats:sup>2</jats:sup>)H and C(sp<jats:sup>3</jats:sup>)H bonds at δ‐ and ε‐positions were effectively activated, thus giving tetrahydroquinolines, benzomorpholines, pyrrolidines, and indolines in moderate to excellent yields by palladium‐catalyzed intramolecular CH amination.</jats:p>
収録刊行物
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- Angewandte Chemie International Edition
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Angewandte Chemie International Edition 53 (37), 9884-9888, 2014-07-22
Wiley