Alzheimer disease: Evidence for selective loss of cholinergic neurons in the nucleus basalis

DOI Web Site Web Site 41 Citations

Description

<jats:title>Abstract</jats:title><jats:p>The nucleus basalis of Meynert provides diffuse cholinergic input to the neocortex. When compared with an age‐ and sex‐matched control, the nucleus basalis from a patient with Alzheimer disease demonstrated substantial reduction of neurons. Loss of this neuronal population may represent an anatomical correlate of the well‐documented cholinergic derangement in Alzheimer disease.</jats:p>

Journal

Citations (41)*help

See more

Details 詳細情報について

Report a problem

Back to top