Clinical and imaging characterization of a patient with idiopathic progressive ataxia and palatal tremor

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Abstract

<jats:p>We describe clinical and imaging features of a patient with sporadic progressive ataxia and palatal tremor (PAPT) of unknown etiology. There was hypertrophy of bilateral inferior olivary nuclei with hyperintense T2‐weighted signal and mild cerebellar atrophy at brain magnetic resonance imaging. 18F‐fluoro‐2‐desoxy‐<jats:sc>d</jats:sc>‐glucose positron emission tomography scanning (FDG‐PET) showed hypometabolism in the red nucleus, external globus pallidus and precuneus while FP‐CIT‐SPECT imaging revealed mild and progressive loss of striatal dopaminergic terminals. Our findings suggest that in idiopathic PAPT involvement of the dentato‐rubro‐olivary pathway occurs along with some dopaminergic dysfunction.</jats:p>

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