Assessing the global threat from Zika virus

DOI Web Site 2 Citations
  • Justin Lessler
    Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
  • Lelia H. Chaisson
    Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
  • Lauren M. Kucirka
    Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
  • Qifang Bi
    Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
  • Kyra Grantz
    Department of Biology, Emerging Pathogens Institute, University of Florida, Gainesville, FL, USA.
  • Henrik Salje
    Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
  • Andrea C. Carcelen
    Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
  • Cassandra T. Ott
    Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
  • Jeanne S. Sheffield
    Department of Gynecology and Obstetrics, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
  • Neil M. Ferguson
    Department of Medicine, School of Public Health, Imperial College London, London, UK.
  • Derek A. T. Cummings
    Department of Biology, Emerging Pathogens Institute, University of Florida, Gainesville, FL, USA.
  • C. Jessica E. Metcalf
    Department of Ecology and Evolutionary Biology, Princeton University, Princeton, NJ, USA.
  • Isabel Rodriguez-Barraquer
    Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.

Description

<jats:title>Global spread of Zika virus</jats:title> <jats:p>Zika virus was identified in Uganda in 1947; since then, it has enveloped the tropics, causing disease of varying severity. Lessler et al. review the historical literature to remind us that Zika's neurotropism was observed in mice even before clinical case reports in Nigeria in 1953. What determines the clinical manifestations; how local conditions, vectors, genetics, and wild hosts affect transmission and geographical spread; what the best control strategy is; and how to develop effective drugs, vaccines, and diagnostics are all critical questions that are begging for data.</jats:p> <jats:p> <jats:italic>Science</jats:italic> , this issue p. <jats:related-article issue="6300" page="663" related-article-type="in-this-issue" vol="353">663</jats:related-article> </jats:p>

Journal

  • Science

    Science 353 (6300), aaf8160-, 2016-08-12

    American Association for the Advancement of Science (AAAS)

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