The Hematologic Aspects of Disseminated (Systemic) Lupus Erythematosus

DOI PDF 被引用文献1件
  • SIDNEY R. MICHAEL
    Medical Services and the Hematology Laboratory of the Division of Laboratories of The Mount Sinai Hospital, New York City.
  • I. LUTFI VURAL
    Medical Services and the Hematology Laboratory of the Division of Laboratories of The Mount Sinai Hospital, New York City.
  • FRANK A. BASSEN
    Medical Services and the Hematology Laboratory of the Division of Laboratories of The Mount Sinai Hospital, New York City.
  • LOUIS SCHAEFER
    Medical Services and the Hematology Laboratory of the Division of Laboratories of The Mount Sinai Hospital, New York City.
  • MILDRED BERGMAN
    Medical Services and the Hematology Laboratory of the Division of Laboratories of The Mount Sinai Hospital, New York City.
  • LOIS LANDIN
    Medical Services and the Hematology Laboratory of the Division of Laboratories of The Mount Sinai Hospital, New York City.
  • HELEN MICHAEL
    Medical Services and the Hematology Laboratory of the Division of Laboratories of The Mount Sinai Hospital, New York City.

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<jats:title>Abstract</jats:title> <jats:p>1. The hematologic data in 111 cases of disseminated (systemic) lupus erythematosus are presented.</jats:p> <jats:p>2. Anemia occurred in practically all patients at some time during their course.</jats:p> <jats:p>3. Leukopenia was seen initially in about one-third of the patients and developed subsequently in about one-half at some time during their course. Many responded to infection with leukocytosis.</jats:p> <jats:p>4. Thrombocytopenia occurred its about one-third of the patients on initial counts and developed subsequently in about one-half at some time its their course. Thrombocytopenia was often seen without leukopenia. Marked thrombocytopenia, simulating "idiopathic" thrombocytopenia purpura, was seen in two cases.</jats:p> <jats:p>5. There was poor correlation between splenomegaly and a reduction in the formed elements of the blood.</jats:p> <jats:p>6. Bone marrow differential counts were not helpful in making the diagnosis but an increase in plasma cells was frequent.</jats:p> <jats:p>7. The Hargraves test was an extremely valuable diagnostic aid.</jats:p> <jats:p>8. Treatment with ACTH and cortisone did not produce any striking hematologic changes.</jats:p> <jats:p>9. Five cases of unusual interest, including three with hemolytic anemia, were presented.</jats:p>

収録刊行物

  • Blood

    Blood 6 (11), 1059-1072, 1951-11-01

    American Society of Hematology

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