A Review: The Pharmacology of Isoliquiritigenin

DOI Web Site Web Site 被引用文献3件
  • Fu Peng
    School of Chinese Medicine The University of Hong Kong 10 Sassoon Road Pokfulam Hong Kong
  • Qiaohui Du
    Chengdu University of Traditional Chinese Medicine Chengdu 610075 China
  • Cheng Peng
    Chengdu University of Traditional Chinese Medicine Chengdu 610075 China
  • Neng Wang
    School of Chinese Medicine The University of Hong Kong 10 Sassoon Road Pokfulam Hong Kong
  • Hailin Tang
    School of Chinese Medicine The University of Hong Kong 10 Sassoon Road Pokfulam Hong Kong
  • Xiaoming Xie
    Department of Breast Oncology, Sun Yat‐Sen University Cancer Center, State Key Laboratory of Oncology in South China Collaborative Innovation Center for Cancer Medicine Guangzhou Guangdong China
  • Jiangang Shen
    School of Chinese Medicine The University of Hong Kong 10 Sassoon Road Pokfulam Hong Kong
  • Jianping Chen
    School of Chinese Medicine The University of Hong Kong 10 Sassoon Road Pokfulam Hong Kong

抄録

<jats:p>Isoliquiritigenin (ISL) is one of the bioactive ingredients isolated from the roots of plants belonging to licorice, including <jats:italic>Glycyrrhiza uralensis</jats:italic>, <jats:italic>Mongolian glycyrrhiza</jats:italic>, <jats:italic>Glycyrrhiza glabra</jats:italic>, and so forth. Liquiritigenin is available in common foods and alternative medicine, and its derivative‐ISL is applied into food additives and disease treatment like cancer therapy, antibiotic therapy, and so on. This review aims at providing a comprehensive summary of the pharmacological activities of ISL. The information published between 1972 and 2014 from a number of reliable sources including PubMed, ScienceDirect, Springer, and Wiley‐Blackwell. The practical application of ISL on the various disease prevention and treatments may stem from its numerous pharmacological properties such as antiinflammatory, anti‐microbial, anti‐oxidative, anticancer activities, immunoregulatory, hepatoprotective, and cardioprotective effects. However, further studies are needed to verify the target‐organ toxicity or side effects investigation. Copyright © 2015 John Wiley & Sons, Ltd.</jats:p>

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