Comparison of Labial Minor Salivary Gland Biopsies from Childhood Sjögren Syndrome and Age-matched Controls
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説明
<jats:sec><jats:title>Objective.</jats:title><jats:p>To determine an appropriate focus score cutoff for childhood Sjögren syndrome (SS).</jats:p></jats:sec><jats:sec><jats:title>Methods.</jats:title><jats:p>Labial salivary gland tissue from specimens from children with SS and age-matched controls was retrospectively identified and reviewed by a blinded oral pathologist.</jats:p></jats:sec><jats:sec><jats:title>Results.</jats:title><jats:p>The presence of any focal sialadenitis (focus score > 0 foci/4 mm<jats:sup>2</jats:sup>) was common among childhood SS samples but present in only 1 of 8 control samples.</jats:p></jats:sec><jats:sec><jats:title>Conclusion.</jats:title><jats:p>The presence of any focal lymphocytic sialadenitis in minor labial salivary gland tissue is suggestive of childhood SS and should be included in future childhood SS-specific diagnostic or classification criteria.</jats:p></jats:sec>
収録刊行物
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- The Journal of Rheumatology
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The Journal of Rheumatology 41 (6), 1178-1182, 2014-05-01
The Journal of Rheumatology