The KCNQ1 Potassium Channel: From Gene to Physiological Function

DOI Web Site 被引用文献6件
  • Thomas Jespersen
    Department of Medical Physiology and Danish Arrhythmia Research Center, The Panum Institute, University of Copenhagen, Copenhagen, Denmark, and
  • Morten Grunnet
    Department of Medical Physiology and Danish Arrhythmia Research Center, The Panum Institute, University of Copenhagen, Copenhagen, Denmark, and
  • Søren-Peter Olesen
    Department of Medical Physiology and Danish Arrhythmia Research Center, The Panum Institute, University of Copenhagen, Copenhagen, Denmark, and

説明

<jats:p>The voltage-gated KCNQ1 (KvLQT1, Kv7.1) potassium channel plays a crucial role in shaping the cardiac action potential as well as in controlling the water and salt homeostasis in several epithelial tissues. KCNQ1 channels in these tissues are tightly regulated by auxiliary proteins and accessory factors, capable of modulating the properties of the channel complexes. This paper reviews the current knowledge about the KCNQ1 channel with a major focus on interacting proteins and physiological functions.</jats:p>

収録刊行物

  • Physiology

    Physiology 20 (6), 408-416, 2005-12

    American Physiological Society

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