Personalized Epigenomic Signatures That Are Stable Over Time and Covary with Body Mass Index

DOI Web Site 2 Citations
  • Andrew P. Feinberg
    Center for Epigenetics, Johns Hopkins School of Medicine, Baltimore, MD 21205, USA.
  • Rafael A. Irizarry
    Center for Epigenetics, Johns Hopkins School of Medicine, Baltimore, MD 21205, USA.
  • Delphine Fradin
    Center for Epigenetics, Johns Hopkins School of Medicine, Baltimore, MD 21205, USA.
  • Martin J. Aryee
    Center for Epigenetics, Johns Hopkins School of Medicine, Baltimore, MD 21205, USA.
  • Peter Murakami
    Center for Epigenetics, Johns Hopkins School of Medicine, Baltimore, MD 21205, USA.
  • Thor Aspelund
    Icelandic Heart Association, Kopavogur 201, Iceland.
  • Gudny Eiriksdottir
    Icelandic Heart Association, Kopavogur 201, Iceland.
  • Tamara B. Harris
    Intramural Research Program, National Institute of Aging, Bethesda, MD 21205, USA.
  • Lenore Launer
    Intramural Research Program, National Institute of Aging, Bethesda, MD 21205, USA.
  • Vilmundur Gudnason
    Icelandic Heart Association, Kopavogur 201, Iceland.
  • M. Daniele Fallin
    Center for Epigenetics, Johns Hopkins School of Medicine, Baltimore, MD 21205, USA.

Description

<jats:p>A genome-scale, gene-specific analysis of DNA methylation in the same individuals over a decade apart identifies a personalized epigenomic signature that may correlate with a common genetic trait.</jats:p>

Journal

  • Science Translational Medicine

    Science Translational Medicine 2 (49), 49ra67-, 2010-09-15

    American Association for the Advancement of Science (AAAS)

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