Absorption and urinary excretion of procyanidin B2 [epicatechin-(4β-8)-epicatechin] in rats
説明
We evaluated the bioavailability and plasma antioxidative activity after administration of procyanidin B2 [epicatechin-(4beta-8)-epicatechin] in rats. After procyanidin B2 administration, procyanidin B2 is absorbed and excreted in urine, and a portion of the PB2 is degraded to (-)-epicatechin and to the metabolized conjugated and/or methylated (-)-epicatechin internally in the rat. Moreover, PB2 reduces the accumulation of lipid peroxide in plasma oxidized by copper ions.
収録刊行物
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- Free Radical Biology and Medicine
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Free Radical Biology and Medicine 33 (1), 142-148, 2002-07
Elsevier BV