Eph receptors and ephrins: effectors of morphogenesis

DOI PDF 被引用文献6件
  • Nigel Holder
    University College 1 Department of Anatomy and Developmental Biology , , Gower Street, London, WC1 6BT, UK
  • Rüdiger Klein
    2 European Molecular Biology Laboratory, Meyerhofstrasse 1, D-69117 Heidelberg, Germany

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公開日
1999-05-15
権利情報
  • http://www.biologists.com/user-licence-1-1/
DOI
  • 10.1242/dev.126.10.2033
公開者
The Company of Biologists

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説明

<jats:title>ABSTRACT</jats:title> <jats:p>Eph receptor tyrosine kinases and their ligands, the ephrins, appear to lie functionally at the interface between pattern formation and morphogenesis. We review the role of Eph and ephrin signalling in the formation of segmented structures, in the control of axon guidance and cell migration and in the development of the vasculature. We address the question of how the specificity of response is achieved and discuss the specificity of ephrin-Eph interactions and the significance of structural domains in Eph receptors.</jats:p>

収録刊行物

  • Development

    Development 126 (10), 2033-2044, 1999-05-15

    The Company of Biologists

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