Exoenzyme S of Pseudomonas aeruginosa ADP-ribosylates the intermediate filament protein vimentin

  • J Coburn
    Department of Molecular Biology and Microbiology, Tufts University School of Medicine, Boston, Massachusetts.
  • S T Dillon
    Department of Molecular Biology and Microbiology, Tufts University School of Medicine, Boston, Massachusetts.
  • B H Iglewski
    Department of Molecular Biology and Microbiology, Tufts University School of Medicine, Boston, Massachusetts.
  • D M Gill
    Department of Molecular Biology and Microbiology, Tufts University School of Medicine, Boston, Massachusetts.

書誌事項

公開日
1989-03
権利情報
  • https://journals.asm.org/non-commercial-tdm-license
DOI
  • 10.1128/iai.57.3.996-998.1989
公開者
American Society for Microbiology

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説明

<jats:p>Exoenzyme S, which had been thought to be unselective, catalyzes the ADP-ribosylation of only a subset of cellular proteins. The intermediate filament protein vimentin is one of the more abundant substrates. Disassembled vimentin, and proteolytic fragments of vimentin that cannot form filaments, is more readily ADP-ribosylated than is filamentous vimentin.</jats:p>

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