UV–Vis–NIR Full‐Range Responsive Carbon Dots with Large Multiphoton Absorption Cross Sections and Deep‐Red Fluorescence at Nucleoli and In Vivo
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- Lei Jiang
- School of Chemistry and Chemical Engineering Anhui University 111 Jiulong Road Hefei 230601 China
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- Haizhen Ding
- School of Chemistry and Chemical Engineering Anhui University 111 Jiulong Road Hefei 230601 China
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- Mingsheng Xu
- School of Chemistry and Chemical Engineering Anhui University 111 Jiulong Road Hefei 230601 China
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- Xiaolong Hu
- School of Chemistry and Chemical Engineering Anhui University 111 Jiulong Road Hefei 230601 China
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- Shengli Li
- School of Chemistry and Chemical Engineering Anhui University 111 Jiulong Road Hefei 230601 China
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- Mingzhu Zhang
- School of Chemistry and Chemical Engineering Anhui University 111 Jiulong Road Hefei 230601 China
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- Qiong Zhang
- School of Chemistry and Chemical Engineering Anhui University 111 Jiulong Road Hefei 230601 China
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- Qiyang Wang
- School of Chemistry and Chemical Engineering Anhui University 111 Jiulong Road Hefei 230601 China
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- Siyu Lu
- College of Chemistry Zhengzhou University 100 Kexue Road Zhengzhou 450001 China
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- Yupeng Tian
- School of Chemistry and Chemical Engineering Anhui University 111 Jiulong Road Hefei 230601 China
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- Hong Bi
- School of Chemistry and Chemical Engineering Anhui University 111 Jiulong Road Hefei 230601 China
書誌事項
- 公開日
- 2020-04-13
- 権利情報
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- http://onlinelibrary.wiley.com/termsAndConditions#vor
- DOI
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- 10.1002/smll.202000680
- 公開者
- Wiley
この論文をさがす
説明
<jats:title>Abstract</jats:title><jats:p>Carbon dots (CDs), with excellent optical property and cytocompatibility, are an ideal class of nanomaterials applied in the field of biomedicine. However, the weak response of CDs in the near‐infrared (NIR) region impedes their practical applications. Here, UV–vis–NIR full‐range responsive fluorine and nitrogen doped CDs (N‐CDs‐F) are designed and synthesized that own a favorable donor‐π‐acceptor (D‐π‐A) configuration and exhibit excellent two‐photon (λ<jats:sub>ex</jats:sub> = 1060 nm), three‐photon (λ<jats:sub>ex</jats:sub> = 1600 nm), and four‐photon (λ<jats:sub>ex</jats:sub> = 2000 nm) excitation upconversion fluorescence. D‐π‐A‐conjugated CDs prepared by solvothermal synthesis under the assistance of ammonia fluoride are reported and are endowed with larger multiphoton absorption (MPA) cross sections (3PA: 9.55 × 10<jats:sup>−80</jats:sup> cm<jats:sup>6</jats:sup> s<jats:sup>2</jats:sup> photon<jats:sup>−2</jats:sup>, 4PA: 6.32 × 10<jats:sup>−80</jats:sup> cm<jats:sup>8</jats:sup> s<jats:sup>3</jats:sup> photon<jats:sup>−3</jats:sup>) than conventional organic compounds. Furthermore, the N‐CDs‐F show bright deep‐red to NIR fluorescence both in vitro and in vivo, and can even stain the nucleoli of tumor cells. A plausible mechanism is proposed on the basis of the strong inter‐dot and intra‐dot hydrogen bonds through NH···F that can facilitate the expanding of conjugated sp<jats:sup>2</jats:sup> domains, and thus not only result in lower highest occupied molecular orbital‐lowest unoccupied molecular orbital energy level but also larger MPA cross sections than those of undoped CDs.</jats:p>
収録刊行物
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- Small
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Small 16 (19), 2000680-, 2020-04-13
Wiley
